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Neuronal acetylcholine receptor subunit alpha-3

Summary

UniProt ID

Q8R4G9

Gene Symbol

Chrna3

Gene ID

110834

Organism

Mus musculus (house mouse)

External Links

PubChem: Q8R4G9
Re-Glyco: Q8R4G9

Annotation

Keyword

Cell membrane
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Golgi apparatus
Ligand-gated ion channel
Phosphoprotein
Postsynaptic cell membrane
Receptor
Reference proteome
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
cholinergic synapse
postsynaptic specialization membrane
postsynaptic membrane
endoplasmic reticulum
Golgi apparatus
acetylcholine-gated channel complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 10** entries
GO Term
regulation of muscle contraction
regulation of smooth muscle contraction
synaptic transmission, cholinergic
locomotory behavior
regulation of acetylcholine secretion, neurotransmission
regulation of membrane potential
behavioral response to nicotine
excitatory postsynaptic potential
synaptic transmission involved in micturition
regulation of dendrite morphogenesis

Displaying **all 3** entries
GO Term
transmembrane signaling receptor activity
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
acetylcholine-gated monoatomic cation-selective channel activity

Annotation information from UniProt.

Sequence

MGVVLPPPPLSMLMLVLMLLPVASASEAEHRLFQYLFEDYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPTWVKAVFLNLLPRVMFMTRPTSTEEDAPKTRNFYGAELSNLNCFSRADSKSCKEGYPCQDGTCGYCHHRRVKISNFSANLTRSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQPLMARDDT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
49	N-linked (GlcNAc...) asparagine			UniProt
166	N-linked (GlcNAc...) asparagine			UniProt

Feature

Domains & sites

PTM

ProtVista

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Highly calcium permeable nicotinic acetylcholine receptors	Mus musculus
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Mus musculus
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements