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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor substrate 2
Summary
- UniProt ID
- Q8WU20
- Gene Symbol
-
- FRS2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Membrane
- Myristate
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| adherens junction |
| cytoplasm |
| plasma membrane |
| cell-cell junction |
| endomembrane system |
| membrane |
Sequence
MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPSVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWEARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIEYSRRRDCTPTVFNFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTDLPM
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 177 |
|
|||
| 256 |
|
|
||
| 329 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activated NTRK2 signals through FRS2 and FRS3 | Homo sapiens |
| Constitutive Signaling by Aberrant PI3K in Cancer | Homo sapiens |
| FRS-mediated FGFR1 signaling | Homo sapiens |
| FRS-mediated FGFR2 signaling | Homo sapiens |
| FRS-mediated FGFR3 signaling | Homo sapiens |
| FRS-mediated FGFR4 signaling | Homo sapiens |
| Frs2-mediated activation | Homo sapiens |
| Negative regulation of FGFR1 signaling | Homo sapiens |
| Negative regulation of FGFR2 signaling | Homo sapiens |
| Negative regulation of FGFR3 signaling | Homo sapiens |
