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TGF-beta receptor type-2

Summary

UniProt ID

Q90999

Gene Symbol

TGFBR2

Gene ID

396399

Organism

Gallus gallus (chicken)

External Links

PubChem: Q90999
Re-Glyco: Q90999

Annotation

Keyword

3D-structure
ATP-binding
Apoptosis
Cell membrane
Differentiation
Disulfide bond
Glycoprotein
Growth regulation
Magnesium
Manganese
Metal-binding
Phosphoprotein
Receptor
Reference proteome
Serine/threonine-protein kinase
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
membrane
extracellular matrix
receptor complex
external side of plasma membrane
caveola
membrane raft
plasma membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 28 in total

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GO Term
positive regulation of reactive oxygen species metabolic process
response to hypoxia
cell activation
apoptotic process
cell-cell junction organization
positive regulation of stress fiber assembly
cardiac epithelial to mesenchymal transition
face morphogenesis
cellular response to growth factor stimulus
positive regulation of tight junction disassembly

Displaying entries **1 - 10** of 17 in total

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GO Term
SMAD binding
activin binding
transforming growth factor beta binding
transforming growth factor beta receptor activity, type III
BMP receptor activity
metal ion binding
activin receptor activity, type I
activin receptor activity, type II
transmembrane receptor protein serine/threonine kinase activity
transforming growth factor beta receptor activity

Annotation information from UniProt.

Sequence

MPPRLRPLLLRVSLWVLVGSSSPALLHDRSKENGLQLPRLCKFCDVKATTCSNQDQCKSNCNITSICEKNNEVCAAVWRRNDENVTLETICHDPQKRLYGHMLDDSSSEQCVMKEKKDDGGLMFMCSCTGEECNDVLIFSAIDPHKPEEKDEISKVTIISLVPLLVISVAVIVIFYAYRTHKKRKLNKAWEKNVKPKKHKDCSDVCAIMLDDDHSDISSTCANNINHNTELLPIELDIVVGKGRFAEVYKAKLKQNTSEQYETVAVKIFPYEEYASWKTEKDIFSDVNLKHENILQFLTAEERKTDLGKQYWLITAFHARGNLQEYLTRHIISWEDLWKLGGSLARGIAHLHSDHTPCGRPKTPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPSLSVDDLANSGQVGTARYMAPEVLESRMNLENMESFKQTDVYSMALVLWEMTSRCNGVGEVKEYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSSWLNHQGIQMVCETLIECWDHDPEARLTAQCVAERFSEFKHHDKLSGRSCSEEKIPEDGSVTTAK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
62	N-linked (GlcNAc...) asparagine			UniProt
84	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Downregulation of TGF-beta receptor signaling	Gallus gallus
TGF-beta receptor signaling activates SMADs	Gallus gallus
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Gallus gallus
TGFBR3 regulates TGF-beta signaling	Gallus gallus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements