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CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

Summary

UniProt ID

Q92187

Gene Symbol

PST
PST1
SIAT8D
ST8SIA4

Gene ID

7903

Organism

Homo sapiens (human)

External Links

GlycoProtDB: GPDB0012443
GlyGen: Q92187
The Human Metabolome Database: HMDBP14324
Re-Glyco: Q92187

Annotation

Keyword

3D-structure
Alternative splicing
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Secreted
Signal-anchor
Transmembrane helix

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
extracellular region
Golgi membrane
Golgi apparatus

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 7** entries
GO Term
protein glycosylation
nervous system development
protein modification process
N-glycan processing
oligosaccharide metabolic process
sialylation
ganglioside biosynthetic process

Displaying **all 3** entries
GO Term
sialyltransferase activity
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
sialic acid binding

Annotation information from UniProt.

Sequence

MRSIRKRWTICTISLLLIFYKTKEIARTEEHQETQLIGDGELSLSRSLVNSSDKIIRKAGSSIFQHNVEGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCVKQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
50	N-linked (GlcNAc...) asparagine		G83460ZZ G80920RR G62765YT	UniProt GlyGen
74	N-linked (GlcNAc...) asparagine	11279095	G83460ZZ	UniProt GlyGen
119	N-linked (GlcNAc...) asparagine		G62765YT	UniProt GlyGen
185			G57321FI	GlyGen
204	N-linked (GlcNAc...) asparagine		G92551JA	UniProt GlyGen
219	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen