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Ubiquitin carboxyl-terminal hydrolase BAP1
Summary
- UniProt ID
- Q92560
- Gene Symbol
-
- BAP1
- KIAA0272
- hucep-6
- Gene ID
- 8314
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Chromatin regulator
- Chromosome
- Coiled coil
- Cytoplasm
- Developmental protein
- Differentiation
- Disease variant
- Intellectual disability
- Nucleus
- Phosphoprotein
- Reference proteome
- Thiol protease
- Ubl conjugation
- Ubl conjugation pathway
- Gene Ontology (GO)
| GO Term |
|---|
| nucleoplasm |
| cytosol |
| PR-DUB complex |
| nucleus |
| chromosome |
| cytoplasm |
| GO Term |
|---|
| histone H2A deubiquitinase activity |
| chromatin binding |
| cysteine-type deubiquitinase activity |
| peptidase activity |
| chromatin DNA binding |
Sequence
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 487 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | Homo sapiens |
| UCH proteinases | Homo sapiens |
