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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
GPI-anchor transamidase
Summary
- UniProt ID
- Q92643
- Gene Symbol
-
- PIGK
- GPI8
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q92643
- PubChem
- Q92643
- The Human Metabolome Database
- HMDBP11012
- RaftProt
- Q92643
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Epilepsy
- GPI-anchor biosynthesis
- Intellectual disability
- Reference proteome
- Signal
- Thiol protease
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| proteolysis |
| attachment of GPI anchor to protein |
| GO Term |
|---|
| membrane |
| GPI-anchor transamidase complex |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| protein disulfide isomerase activity |
| GPI-anchor transamidase activity |
Sequence
MAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVFSHKNMELNVYGDDVEVDYRSYEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQIIHQKPKLKDWHPPGGFILGLWALIIMVFFKTYGIKHMKFIF
Glycosylation Sites
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Attachment of GPI anchor to uPAR | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3571 | liver cancer | |
| DOID:0060058 | lymphoma | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:162 | cancer | |
| DOID:3234 | central nervous system lymphoma | |
| DOID:5672 | large intestine cancer | |
| DOID:5825 | adult lymphoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:8675 | obsolete ymphosarcoma | |
| DOID:9256 | colorectal cancer |
