Methionine--tRNA ligase, mitochondrial

Summary
UniProt ID
Q96GW9
Gene Symbol
  • MARS2
Organism
Homo sapiens (human)
GlyGen
Q96GW9
PubChem
Q96GW9
The Human Metabolome Database
HMDBP09251
The O-GlcNAc Database
Q96GW9
O-GlcNAcAtlas
Q96GW9
Annotation
Keyword
  • ATP-binding
  • Aminoacyl-tRNA synthetase
  • Deafness
  • Disease variant
  • Mitochondrion
  • Neurodegeneration
  • Primary mitochondrial disease
  • Protein biosynthesis
  • Reference proteome
  • Transit peptide
Gene Ontology (GO)
Displaying 1 entry
GO Term
mitochondrial matrix
Displaying all 2 entries
GO Term
methionine-tRNA ligase activity
ATP binding
Sequence
MLRTSVLRLLGRTGASRLSLLEDFGPRYYSSGSLSAGDDACDVRAYFTTPIFYVNAAPHIGHLYSALLADALCRHRRLRGPSTAATRFSTGTDEHGLKIQQAAATAGLAPTELCDRVSEQFQQLFQEAGISCTDFIRTTEARHRVAVQHFWGVLKSRGLLYKGVYEGWYCASDECFLPEAKVTQQPGPSGDSFPVSLESGHPVSWTKEENYIFRLSQFRKPLQRWLRGNPQAITPEPFHHVVLQWLDEELPDLSVSRRSSHLHWGIPVPGDDSQTIYVWLDALVNYLTVIGYPNAEFKSWWPATSHIIGKDILKFHAIYWPAFLLGAGMSPPQRICVHSHWTVCGQKMSKSLGNVVDPRTCLNRYTVDGFRYFLLRQGVPNWDCDYYDEKVVKLLNSELADALGGLLNRCTAKRINPSETYPAFCTTCFPSEPGLVGPSVRAQAEDYALVSAVATLPKQVADHYDNFRIYKALEAVSSCVRQTNGFVQRHAPWKLNWESPVDAPWLGTVLHVALECLRVFGTLLQPVTPSLADKLLSRLGVSASERSLGELYFLPRFYGHPCPFEGRRLGPETGLLFPRLDQSRTWLVKAHRT
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
131
528
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Mitochondrial tRNA aminoacylation Homo sapiens

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024