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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Peroxisomal acyl-coenzyme A oxidase 2
Summary
- UniProt ID
- Q99424
- Gene Symbol
-
- ACOX2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q99424
- PubChem
- Q99424
- The Human Metabolome Database
- HMDBP00164
- The O-GlcNAc Database
- Q99424
- O-GlcNAcAtlas
- Q99424
Annotation
- Keyword
-
- Direct protein sequencing
- Disease variant
- FAD
- Fatty acid metabolism
- Oxidoreductase
- Peroxisome
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| bile acid biosynthetic process |
| lipid homeostasis |
| very long-chain fatty acid metabolic process |
| fatty acid beta-oxidation using acyl-CoA oxidase |
| GO Term |
|---|
| intracellular membrane-bounded organelle |
| peroxisome |
| cytosol |
| peroxisomal matrix |
Sequence
MGSPVHRVSLGDTWSRQMHPDIESERYMQSFDVERLTNILDGGAQNTALRRKVESIIHSYPEFSCKDNYFMTQNERYKAAMRRAFHIRLIARRLGWLEDGRELGYAYRALSGDVALNIHRVFVRALRSLGSEEQIAKWDPLCKNIQIIATYAQTELGHGTYLQGLETEATYDAATQEFVIHSPTLTATKWWPGDLGRSATHALVQAQLICSGARRGMHAFIVPIRSLQDHTPLPGIIIGDIGPKMDFDQTDNGFLQLNHVRVPRENMLSRFAQVLPDGTYVKLGTAQSNYLPMVVVRVELLSGEILPILQKACVIAMRYSVIRRQSRLRPSDPEAKVLDYQTQQQKLFPQLAISYAFHFLAVSLLEFFQHSYTAILNQDFSFLPELHALSTGMKAMMSEFCTQGAEMCRRACGGHGYSKLSGLPSLVTKLSASCTYEGENTVLYLQVARFLVKSYLQTQMSPGSTPQRSLSPSVAYLTAPDLARCPAQRAADFLCPELYTTAWAHVAVRLIKDSVQHLQTLTQSGADQHEAWNQTTVIHLQAAKVHCYYVTVKGFTEALEKLENEPAIQQVLKRLCDLHAIHGILTNSGDFLHDAFLSGAQVDMARTAYLDLLRLIRKDAILLTDAFDFTDQCLNSALGCYDGNVYERLFQWAQKSPTNTQENPAYEEYIRPLLQSWRSKL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 556 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Beta-oxidation of pristanoyl-CoA | Homo sapiens |
| Peroxisomal protein import | Homo sapiens |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080476 | peroxisome biogenesis disorder 1A | |
| DOID:0111067 | congenital bile acid synthesis defect 6 | |
| DOID:10602 | obsolete steatorrhea | |
| DOID:114 | heart disease | |
| DOID:1287 | cardiovascular system disease | |
| DOID:1612 | breast cancer | |
| DOID:3459 | breast carcinoma | |
| DOID:3571 | liver cancer | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:687 | hepatoblastoma |
