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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
E3 ubiquitin-protein ligase RING2
Summary
- UniProt ID
- Q99496
- Gene Symbol
-
- RNF2
- BAP1
- DING
- HIPI3
- RING1B
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q99496
- PubChem
- Q99496
- The Human Metabolome Database
- HMDBP11563
- The O-GlcNAc Database
- Q99496
- O-GlcNAcAtlas
- Q99496
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Chromosome
- Cytoplasm
- Disease variant
- Epilepsy
- Intellectual disability
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Reference proteome
- Repressor
- Transcription regulation
- Transferase
- Ubl conjugation
- Ubl conjugation pathway
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| PcG protein complex |
| sex chromatin |
| ubiquitin ligase complex |
| nucleoplasm |
| nuclear body |
| PRC1 complex |
| MLL1 complex |
| euchromatin |
| nucleus |
| cytoplasm |
| GO Term |
|---|
| chromatin binding |
| histone H2AK119 ubiquitin ligase activity |
| zinc ion binding |
| ubiquitin protein ligase activity |
| RING-like zinc finger domain binding |
Sequence
MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCSNASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
Glycosylation Sites
G62765YT
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Oxidative Stress Induced Senescence | Homo sapiens |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | Homo sapiens |
| Regulation of PTEN gene transcription | Homo sapiens |
| SUMOylation of DNA damage response and repair proteins | Homo sapiens |
| SUMOylation of DNA methylation proteins | Homo sapiens |
| SUMOylation of RNA binding proteins | Homo sapiens |
| SUMOylation of chromatin organization proteins | Homo sapiens |
| SUMOylation of transcription cofactors | Homo sapiens |
| Transcriptional Regulation by E2F6 | Homo sapiens |
