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Histidine-rich glycoprotein

Summary

UniProt ID

Q99PS8

Gene Symbol

Hrg
Hrg1

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q99PS8

Annotation

Keyword

Cleavage on pair of basic residues
Copper
Disulfide bond
Fibrinolysis
Glycoprotein
Heparin-binding
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal
Zinc

Gene Ontology (GO)

Displaying entries **1 - 10** of 25 in total

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GO Term
negative regulation of cell adhesion
negative regulation of cell population proliferation
regulation of gene expression
positive regulation of immune response to tumor cell
negative regulation of lamellipodium assembly
heme transport
negative regulation of cell adhesion mediated by integrin
fibrinolysis
negative regulation of vascular endothelial growth factor signaling pathway
antimicrobial humoral immune response mediated by antimicrobial peptide

Displaying **all 4** entries
GO Term
extracellular region
cell surface
endolysosome
blood microparticle

Displaying **all 9** entries
GO Term
metal ion binding
heme binding
heparan sulfate proteoglycan binding
serine-type endopeptidase inhibitor activity
signaling receptor binding
heparin binding
cysteine-type endopeptidase inhibitor activity
immunoglobulin binding
zinc ion binding

Annotation information from UniProt.

Sequence

MKVLTTALLLVTLQCSHALSPTNCDASKPLAEKVLDLINKGRRSGYTFQLLRVSDAHLDRVETATIYYLVLDVVESDCWVLSTKAQDECLPAMRTSEVVIGQCKVIATRYSNESQDLSVNGYNCTMRSVSSAYINTKDSPVLVDSFEDSEPYRKLARKALDKYKAENGDFASFRVERAERVIRMRGGERTSYFIEFSVRNCSTQHFPRHPPVFGLCRVVLTYSTEASDLETPEYTDLICEVFNTEDLKNRSDMKPHRGHEHPHCDKHLCKLSGPRDHHHTHKTHEIGCPPPPEGKDNSDRPPLQEGALPQMLPGHSGPSGTNRSHRPPHNHSCNEHPCHGQHPHGHHPHGQHPHGHHPHGQHPHGHHPHGQHPHGHHPHGQHPHGHHPHGHHPHGDHPHGHHPHGHDFLDYGPCDPPSNSQELKGQYHRGHGPPHGHSRKRGPGKGLFPFHQRQIGYVYRLPPLNVGEVLTPPEANFPIFSLPNCNRPPQPEIRPFPQTASKSCPGKFEGKFPQVSNFFEHTPPK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
112	N-linked (GlcNAc...) asparagine	UniProt
123	N-linked (GlcNAc...) asparagine	UniProt
200	N-linked (GlcNAc...) asparagine	UniProt
322	N-linked (GlcNAc...) asparagine	UniProt
330	N-linked (GlcNAc...) asparagine	UniProt