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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Serine/threonine-protein kinase PINK1, mitochondrial
Summary
- UniProt ID
- Q9BXM7
- Gene Symbol
-
- PINK1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9BXM7
- PubChem
- Q9BXM7
- The Human Metabolome Database
- HMDBP01217
- The O-GlcNAc Database
- Q9BXM7
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Autophagy
- Cytoplasm
- Disease variant
- Magnesium
- Metal-binding
- Mitochondrion inner membrane
- Mitochondrion outer membrane
- Neurodegeneration
- Parkinson disease
- Parkinsonism
- Phosphoprotein
- Primary mitochondrial disease
- Reference proteome
- Serine/threonine-protein kinase
- Transit peptide
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| mitochondrial inner membrane |
| cytosol |
| endoplasmic reticulum |
| mitochondrial outer membrane |
| mitochondrial intermembrane space |
| perinuclear region of cytoplasm |
| Lewy body |
| GO Term |
|---|
| ATP binding |
| calcium-dependent protein kinase activity |
| protein serine kinase activity |
| TORC2 complex binding |
Sequence
MAVRQALGRGLQLGRALLLRFTGKPGRAYGLGRPGPAAGCVRGERPGWAAGPGAEPRRVGLGLPNRLRFFRQSVAGLAARLQRQFVVRAWGCAGPCGRAVFLAFGLGLGLIEEKQAESRRAVSACQEIQAIFTQKSKPGPDPLDTRRLQGFRLEEYLIGQSIGKGCSAAVYEATMPTLPQNLEVTKSTGLLPGRGPGTSAPGEGQERAPGAPAFPLAIKMMWNISAGSSSEAILNTMSQELVPASRVALAGEYGAVTYRKSKRGPKQLAPHPNIIRVLRAFTSSVPLLPGALVDYPDVLPSRLHPEGLGHGRTLFLVMKNYPCTLRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGKAHLESRSYQEAQLPALPESVPPDVRQLVRALLQREASKRPSARVAANVLHLSLWGEHILALKNLKLDKMVGWLLQQSAATLLANRLTEKCCVETKMKMLFLANLECETLCQAALLLCSWRAAL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 198 |
|
|||
| 199 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FOXO-mediated transcription of cell death genes | Homo sapiens |
| PINK1-PRKN Mediated Mitophagy | Homo sapiens |
