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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Metal cation symporter ZIP8
Summary
- UniProt ID
- Q9C0K1
- Gene Symbol
-
- SLC39A8
- BIGM103
- ZIP8
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9C0K1
- PubChem
- Q9C0K1
- The Human Metabolome Database
- HMDBP11941
- The O-GlcNAc Database
- Q9C0K1
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Congenital disorder of glycosylation
- Glycoprotein
- Lysosome
- Reference proteome
- Signal
- Symport
- Transmembrane helix
- Zinc transport
- Gene Ontology (GO)
| GO Term |
|---|
| lysosomal membrane |
| plasma membrane |
| organelle membrane |
| basolateral plasma membrane |
| apical plasma membrane |
| GO Term |
|---|
| monoatomic cation:bicarbonate symporter activity |
| zinc:bicarbonate symporter activity |
| zinc ion transmembrane transporter activity |
Sequence
MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASRVGVPEPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIELE
Glycosylation Sites
G12270AG
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Zinc influx into cells by the SLC39 gene family | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050835 | generalized dystonia | |
| DOID:0040085 | bacterial sepsis | |
| DOID:0050570 | congenital disorder of glycosylation type I | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050635 | alternating hemiplegia of childhood | |
| DOID:0050741 | alcohol dependence | |
| DOID:0050742 | nicotine dependence | |
| DOID:0050841 | focal hand dystonia | |
| DOID:0060192 | Crohn's colitis | |
| DOID:0060224 | atrial fibrillation |
