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E3 ubiquitin-protein ligase RNF146
Summary
- UniProt ID
- Q9CZW6
- Gene Symbol
-
- Rnf146
- Gene ID
- 68031
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Cytoplasm
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Reference proteome
- Transferase
- Ubl conjugation
- Ubl conjugation pathway
- Wnt signaling pathway
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| nucleoplasm |
| cytosol |
| GO Term |
|---|
| ubiquitin protein ligase activity |
| zinc ion binding |
| poly-ADP-D-ribose binding |
| ubiquitin-protein transferase activity |
Sequence
MEMAGCGEIDHSINMLPTNKKANESCSNTAPSLTVPECAICLQTCVHPVSLPCKHVFCYLCVKGASWLGKRCALCRQEIPEDFLDKPTLLSPEELKAASRGNGEYAWYYEGRNGWWQYDERTSRELEDAFSKGKKNTEMLIAGFLYVADLENMVQYRRNEHGRRRKIKRDIIDIPKKGVAGLRLDCDTNTVNLARESSADGADSGSAQTGASVQLAVPSSTRPLTSVDGQLTSPVTPSPDAGISLEDSFAHLQLSGDSIAERSHRGEGEEDHESPSSGRVPDTSVEETESDASSDSEDAPVVVAQHSLTQQRPLVPNGNQTVADQSDRSGTDRSVAGGGTMSVNVRSRRPDGQCTVTEV
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Degradation of AXIN | Mus musculus |
| Regulation of PTEN stability and activity | Mus musculus |
| TCF dependent signaling in response to WNT | Mus musculus |
| Ub-specific processing proteases | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2256 | osteochondrodysplasia |
