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Toll-like receptor 9

Summary

UniProt ID

Q9EQU3

Gene Symbol

Tlr9

Gene ID

81897

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007509
GlyGen: Q9EQU3
PubChem: Q9EQU3
Re-Glyco: Q9EQU3

Annotation

Keyword

3D-structure
Cytoplasmic vesicle
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
Lysosome
Palmitate
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

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GO Term
early phagosome
lysosome
plasma membrane
endosome
endoplasmic reticulum
endoplasmic reticulum membrane
basolateral plasma membrane
apical plasma membrane
early endosome membrane
endolysosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
male gonad development
positive regulation of cytokine production
positive regulation of immunoglobulin production
immune response
response to virus
positive regulation of B cell proliferation
positive regulation of chemokine production
positive regulation of type II interferon production
innate immune response
regulation of B cell differentiation

Displaying **all 5** entries
GO Term
protein homodimerization activity
siRNA binding
unmethylated CpG binding
pattern recognition receptor activity
interleukin-1 receptor binding

Annotation information from UniProt.

Sequence

MVLRRRTLHPLSLLVQAAVLAETLALGTLPAFLPCELKPHGLVDCNWLFLKSVPRFSAAASCSNITRLSLISNRIHHLHNSDFVHLSNLRQLNLKWNCPPTGLSPLHFSCHMTIEPRTFLAMRTLEELNLSYNGITTVPRLPSSLVNLSLSHTNILVLDANSLAGLYSLRVLFMDGNCYYKNPCTGAVKVTPGALLGLSNLTHLSLKYNNLTKVPRQLPPSLEYLLVSYNLIVKLGPEDLANLTSLRVLDVGGNCRRCDHAPNPCIECGQKSLHLHPETFHHLSHLEGLVLKDSSLHTLNSSWFQGLVNLSVLDLSENFLYESITHTNAFQNLTRLRKLNLSFNYRKKVSFARLHLASSFKNLVSLQELNMNGIFFRLLNKYTLRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRISGPSTLSEATPEEADDAEQEELLSADPHPAPLSTPASKNFMDRCKNFKFTMDLSRNNLVTIKPEMFVNLSRLQCLSLSHNSIAQAVNGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQPFSMKGIGHNFSFVTHLSMLQSLSLAHNDIHTRVSSHLNSNSVRFLDFSGNGMGRMWDEGGLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKLLSLRDNYLSFFNWTSLSFLPNLEVLDLAGNQLKALTNGTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSHNILKTVDRSWFGPIVMNLTVLDVRSNPLHCACGAAFVDLLLEVQTKVPGLANGVKCGSPGQLQGRSIFAQDLRLCLDEVLSWDCFGLSLLAVAVGMVVPILHHLCGWDVWYCFHLCLAWLPLLARSRRSAQTLPYDAFVVFDKAQSAVADWVYNELRVRLEERRGRRALRLCLEDRDWLPGQTLFENLWASIYGSRKTLFVLAHTDRVSGLLRTSFLLAQQRLLEDRKDVVVLVILRPDAHRSRYVRLRQRLCRQSVLFWPQQPNGQGGFWAQLSTALTRDNRHFYNQNFCRGPTAE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
64	N-linked (GlcNAc...) asparagine		G80920RR	GlycoProtDB UniProt GlyGen
129	N-linked (GlcNAc...) asparagine			UniProt GlyGen
147	N-linked (GlcNAc...) asparagine			UniProt GlyGen
191				GlyGen
200	N-linked (GlcNAc...) asparagine		G80920RR	GlycoProtDB UniProt GlyGen
210	N-linked (GlcNAc...) asparagine	25686612		UniProt GlyGen
242	N-linked (GlcNAc...) asparagine		G02886BB	UniProt GlyGen
300	N-linked (GlcNAc...) asparagine			UniProt GlyGen
309	N-linked (GlcNAc...) asparagine			UniProt GlyGen
332	N-linked (GlcNAc...) asparagine	25686612		UniProt GlyGen