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Muscarinic acetylcholine receptor M3

Summary

UniProt ID

Q9ERZ3

Gene Symbol

Chrm-3
Chrm3

Gene ID

12671

Organism

Mus musculus (house mouse)

External Links

PubChem: Q9ERZ3
Re-Glyco: Q9ERZ3

Annotation

Keyword

Cell membrane
Disulfide bond
Endoplasmic reticulum
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Postsynaptic cell membrane
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
plasma membrane
dendrite
endoplasmic reticulum membrane
basolateral plasma membrane
presynaptic membrane
axon terminus
postsynaptic density membrane
glutamatergic synapse

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 12 in total

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2

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GO Term
smooth muscle contraction
synaptic transmission, cholinergic
positive regulation of insulin secretion
positive regulation of smooth muscle contraction
saliva secretion
negative regulation of heart rate by acetylcholine
phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway
ion channel modulating, G protein-coupled receptor signaling pathway
positive regulation of vascular associated smooth muscle contraction
ligand-gated ion channel signaling pathway

Displaying **all 4** entries
GO Term
G protein-coupled acetylcholine receptor activity
G protein-coupled acetylcholine receptor binding
acetylcholine binding
quaternary ammonium group binding

Annotation information from UniProt.

Sequence

MTLHSNSTTSPLFPNISSSWVHSPSEAGLPLGTVSQLDSYNISQTSGNFSSNDTSSDPLGGHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQGTKRSSRRKYGGCHFWFTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPDKDLGTMDVERNAHKLQAQKSMDDRDNCQKDFSKLPIQLESAVDTAKTSDTNSSVDKTTAALPLSFKEATLAKRFALKTRSQITKRKRMSLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
6	N-linked (GlcNAc...) asparagine	UniProt
15	N-linked (GlcNAc...) asparagine	UniProt
41	N-linked (GlcNAc...) asparagine	UniProt
48	N-linked (GlcNAc...) asparagine	UniProt
52	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
G alpha (q) signalling events	Mus musculus
Muscarinic acetylcholine receptors	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060610	megacystis-microcolon-intestinal hypoperistalsis syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements