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MIRAGE
Mannan-binding lectin serine protease 2
Summary
- UniProt ID
- Q9JJS8
- Gene Symbol
-
- Masp2
- Gene ID
- 64459
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Autocatalytic cleavage
- Calcium
- Complement pathway
- Direct protein sequencing
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Hydroxylation
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| GO Term |
|---|
| proteolysis |
| complement activation |
| complement activation, classical pathway |
| complement activation, lectin pathway |
| GO Term |
|---|
| serine-type endopeptidase activity |
| calcium ion binding |
| peptidase activity |
| calcium-dependent protein binding |
| complement component C4b binding |
Sequence
MRLLIVLGLLWSLVATLLGSKWPEPVFGRLVSLGFPEKYGNHQDRSWTLTAPPGFRLRLYFTHFNLELSYRCEYDFVKLTSGTKVLATLCGQESTDTERAPGNDTFYSLGPSLKVTFHSDYSNEKPFTGFEAFYAAEDVDECRTSLGDSVPCDHYCHNYLGGYYCSCRVGYILHQNKHTCSALCSGQVFTGRSGFLSSPEYPQPYPKLSSCAYNIRLEEGFSITLDFVESFDVEMHPEAQCPYDSLKIQTDKREYGPFCGKTLPPRIETDSNKVTITFTTDESGNHTGWKIHYTSTAQPCPDPTAPPNGHISPVQATYVLKDSFSVFCKTGFELLQGSVPLKSFTAVCQKDGSWDRPIPECSIIDCGPPDDLPNGHVDYITGPEVTTYKAVIQYSCEETFYTMSSNGKYVCEADGFWTSSKGEKSLPVCKPVCGLSTHTSGGRIIGGQPAKPGDFPWQVLLLGETTAAGALIHDDWVLTAAHAVYGKTEAMSSLDIRMGILKRLSLIYTQAWPEAVFIHEGYTHGAGFDNDIALIKLKNKVTINRNIMPICLPRKEAASLMKTDFVGTVAGWGLTQKGFLARNLMFVDIPIVDHQKCATAYTKQPYPGAKVTVNMLCAGLDRGGKDSCRGDSGGALVFLDNETQRWFVGGIVSWGSINCGGSEQYGVYTKVTNYIPWIENIINNF
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Rattus norvegicus |
| Initial triggering of complement | Rattus norvegicus |
| Lectin pathway of complement activation | Rattus norvegicus |
