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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Neutral ceramidase
Summary
- UniProt ID
- Q9NR71
- Gene Symbol
-
- ASAH2
- HNAC1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9NR71
- PubChem
- Q9NR71
- SwissLipids
- The Human Metabolome Database
- HMDBP09165
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Apoptosis
- Calcium
- Cell membrane
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Hydrolase
- Metal-binding
- Mitochondrion
- Phosphoprotein
- Reference proteome
- Secreted
- Signal-anchor
- Sphingolipid metabolism
- Transmembrane helix
- Ubl conjugation
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| Golgi apparatus |
| extracellular region |
| mitochondrion |
| plasma membrane |
| caveola |
| extracellular exosome |
| GO Term |
|---|
| N-acylsphingosine amidohydrolase activity |
| ceramidase activity |
| calcium ion binding |
| zinc ion binding |
Sequence
MAKRTFSNLETFLIFLLVMMSAITVALLSLLFITSGTIENHKDLGGHFFSTTQSPPATQGSTAAQRSTATQHSTATQSSTATQTSPVPLTPESPLFQNFSGYHIGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGSNRTVFVSIDIGMVSQRLRLEVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQTFQHMVTGILKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYSSNTDKEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQGPFVAAFASSNLGDVSPNILGPRCINTGESCDNANSTCPIGGPSMCIAKGPGQDMFDSTQIIGRAMYQRAKELYASASQEVTGPLASAHQWVDMTDVTVWLNSTHASKTCKPALGYSFAAGTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEIKECHKPKPILLHTGELSKPHPWHPDIVDVQIITLGSLAITAIPGEFTTMSGRRLREAVQAEFASHGMQNMTVVISGLCNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRNLAKAIATDTVANLSRGPEPPFFKQLIVPLIPSIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNRKQDILKPAVILSFEGTSPAFEVVTI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 62 | O-linked (GalNAc...) threonine |
|
||
| 67 | O-linked (GalNAc...) serine |
|
||
| 68 | O-linked (GalNAc...) threonine |
|
||
| 70 | O-linked (GalNAc...) threonine |
|
||
| 73 | O-linked (GalNAc...) serine |
|
||
| 74 | O-linked (GalNAc...) threonine |
|
||
| 76 | O-linked (GalNAc...) threonine |
|
||
| 78 | O-linked (GalNAc...) serine |
|
||
| 79 | O-linked (GalNAc...) serine |
|
||
| 80 | O-linked (GalNAc...) threonine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Glycosphingolipid catabolism | Homo sapiens |
Human Protein Atlas