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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Rho guanine nucleotide exchange factor 4
Summary
- UniProt ID
- Q9NR80
- Gene Symbol
-
- ARHGEF4
- KIAA1112
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q9NR80
- The Human Metabolome Database
- HMDBP11493
- The O-GlcNAc Database
- Q9NR80
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cell projection
- Cytoplasm
- Guanine-nucleotide releasing factor
- Reference proteome
- SH3 domain
- Gene Ontology (GO)
| GO Term |
|---|
| intracellular signal transduction |
| lamellipodium assembly |
| filopodium assembly |
| regulation of small GTPase mediated signal transduction |
| GO Term |
|---|
| cytosol |
| ruffle membrane |
| GO Term |
|---|
| protein domain specific binding |
| guanyl-nucleotide exchange factor activity |
Sequence
MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPHRSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTAMPDGALDTAVCADEVGSEEDLYDDLHSSSHHYSHPGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPADDDAPLAGNSGAEDGGAEAQSSKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKRADMFSEEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRLDMDGLEVVDLEDGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSITELQRKQAMLNASKQQVTGKPKAVGRPCYLTRQKHPALPSNRPQQQVLVLAEPRRKPSTFWHSISRLAPFRK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 649 |
|
|||
| 658 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CDC42 GTPase cycle | Homo sapiens |
| G alpha (12/13) signalling events | Homo sapiens |
| NRAGE signals death through JNK | Homo sapiens |
| RAC1 GTPase cycle | Homo sapiens |
| RHOA GTPase cycle | Homo sapiens |
