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MIRAGE
Transmembrane protein 106B

Summary
UniProt ID
Q9NUM4
Gene Symbol
  • TMEM106B
Gene ID
54664
Organism
Homo sapiens (human)
GlyConnect
GlyGen
Q9NUM4
The O-GlcNAc Database
Q9NUM4
RaftProt
Q9NUM4
O-GlcNAcAtlas
Q9NUM4
Re-Glyco
Q9NUM4
Annotation
Keyword
  • 3D-structure
  • Amyotrophic lateral sclerosis
  • Cell membrane
  • Disease variant
  • Disulfide bond
  • Endosome
  • Glycoprotein
  • Leukodystrophy
  • Lysosome
  • Myristate
  • Phosphoprotein
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
  • Transport
Gene Ontology (GO)
Displaying all 5 entries
GO Term
lysosome
plasma membrane
endosome
lysosomal membrane
late endosome membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
ATPase binding
Annotation information from UniProt.
Sequence
MGKSLSHLPLHSSKEDAYDGVTSENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITIIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTTYQLGQSEYLNVLQPQQ
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 8 entries
Position Description PubMed ID GlyTouCan ID Source
145 N-linked (GlcNAc...) asparagine
151 N-linked (GlcNAc...) asparagine
164 N-linked (GlcNAc...) asparagine
182
183 N-linked (GlcNAc...) asparagine
185
223
256 N-linked (GlcNAc...) asparagine
Feature
204060801001201401601802002202402601274
20406080100120140160180200220240260MGKSLSHLPLHSSKEDAYDGVTSENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITIIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTTYQLGQSEYLNVLQPQQ
Domains & sites
PTM
ProtVista
20406080100120140160180200220240260MGKSLSHLPLHSSKEDAYDGVTSENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITIIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTTYQLGQSEYLNVLQPQQ
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0070405 hypomyelinating leukodystrophy 16
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025