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Insulin receptor

Summary

UniProt ID

Q9PVZ4

Gene Symbol

insr

Organism

Xenopus laevis (African clawed frog)

External Links

PubChem: Q9PVZ4

Annotation

Keyword

ATP-binding
Cell membrane
Cleavage on pair of basic residues
Developmental protein
Disulfide bond
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
insulin receptor signaling pathway
glucose homeostasis
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
protein autophosphorylation
positive regulation of MAPK cascade

Displaying **all 4** entries
GO Term
plasma membrane
insulin receptor complex
membrane
axon

Displaying **all 9** entries
GO Term
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
insulin receptor activity
insulin binding
PTB domain binding
insulin receptor substrate binding
ATP binding
SH2 domain binding
phosphatidylinositol 3-kinase binding

Annotation information from UniProt.

Sequence

MGQGVLRGEGHPNNNPNSKVGWKSLVGIITIFMLILCDQSDGKICYSMDIRNNISQFSMLEDCTVIEGHLQILLMFTSKPENFRGLRFPKLTTITDYLLLFRVYGLESLKDLFPNLTVIRGTRLFFNYALVIFEMVHXKEIGLYNLMNITRGSVRIEKNNELCYLSTIDWSIILDSVEDNYIELNRDNKEECGDVCPGTVKGKSKCKHTLVNGALVERCWTQDHCQKVCPSDCKGSGCLPDGQCCHPECLGSCRKPNDPSECTACRHFQNEGVCVTACPKGSYQFQGWRCIDFNTCQELNSRCQNSRDNSCPPYVIHKGECMPDCPSGYIANSTTRTCTPCAGPCPKVCTIFQNVKTIDSVTSAQELRGCTVINGSLIINLRGGNNIATELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGEVLEAGNYSFYALDNPSLRQLWDWHKHNLTIIHGKLFFHHNPRLCLSQIHQMEEVTGTKGRQDKNDIATKTNGDQASCEDNLLTFNFIKTSHDMVLLRWDAYWPPDYRDLLGFMVHYKEAPFQNVTEFDGQDACGSNSWTVVDMDAPERSADGKTQSPGCLLRSLKPWTQYAVFVKTLVSGSDEGRTYGAKSKIIYIRTNETIPSVPLDPFSVSNSTSQIILKWKPPSEPNGNVTHYLVYWQEQPEDSDLYEVDYCNKGLKLPSRTWTPPTEIDENGNENQTEHTSVNKCCPCPKTEFQIQKEQDESAFRKTFENYLHNEVFIPRPVRKRRDLFGVANGTLPDPVTAPPLFNVSSTRAPDEPEPKIYSQKVWFKESVLISGLKHFTGYRIEIHACNHELSMGCSVAAYVNARTMPEATADKVVGPITYEYVEPNIIHLKWQEPKDPNGLIVLYEVHYSRVGGIEEVITCVSQKQYNTDKGGKLRVLTPGNYSVKIRATSLAGNGSWTEQAYFQVPDHPHSNIVKIITGPIIAVFLLLIVLVYCVVQKKKDAEGPAGPLYTSSNPEYLSASEVYIPDEWEVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVNESASLRERIEFLNEASVMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYLRSLRPDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMVADDYAVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLKDDLRPSFQDVSFYYSDENKPPETDDLEIDFENMESTPLDPSSCSLRDQSSRTNIYEEHIPYTHMNGGRKNGRILSLPRSSPS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **11 - 16** of 16 in total

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Position	Description	Source
660	N-linked (GlcNAc...) asparagine	UniProt
707	N-linked (GlcNAc...) asparagine	UniProt
765	N-linked (GlcNAc...) asparagine	UniProt
779	N-linked (GlcNAc...) asparagine	UniProt
917	N-linked (GlcNAc...) asparagine	UniProt
930	N-linked (GlcNAc...) asparagine	UniProt