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Core histone macro-H2A.1

Summary

UniProt ID

Q9QZQ8

Gene Symbol

Macroh2a1
H2afy

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9QZQ8
The O-GlcNAc Database: Q9QZQ8
RaftProt: Q9QZQ8

Annotation

Keyword

Acetylation
Alternative splicing
Chromatin regulator
Isopeptide bond
Methylation
Nucleosome core
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation

Gene Ontology (GO)

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GO Term
negative regulation of gene expression, epigenetic
heterochromatin organization
transcription initiation-coupled chromatin remodeling
negative regulation of transcription by RNA polymerase II
regulation of oxidative phosphorylation
DNA repair
nucleosome assembly
sex-chromosome dosage compensation
negative regulation of cell cycle G2/M phase transition
positive regulation of maintenance of mitotic sister chromatid cohesion

Displaying **all 10** entries
GO Term
chromatin
nucleus
nucleolus
nucleosome
condensed chromosome
Barr body
nucleoplasm
pericentric heterochromatin
centrosome
site of DNA damage

Displaying entries **1 - 10** of 12 in total

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GO Term
chromatin binding
protein kinase binding
protein serine/threonine kinase inhibitor activity
promoter-specific chromatin binding
structural constituent of chromatin
nucleosomal DNA binding
protein heterodimerization activity
RNA polymerase II transcription regulatory region sequence-specific DNA binding
rDNA binding
double-stranded methylated DNA binding

Annotation information from UniProt.

Sequence

MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVAKKTGGKKGARKSKKKQGEVSKAASADSTTEGTPTDGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFYTGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAISAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFMLFDSESIGIYVQEMAKLDAN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites