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Homeodomain-interacting protein kinase 2

Summary

UniProt ID

Q9QZR5

Gene Symbol

Hipk2
Nbak1
Stank

Gene ID

15258

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9QZR5
PubChem: Q9QZR5
The O-GlcNAc Database: Q9QZR5
O-GlcNAcAtlas: Q9QZR5
Re-Glyco: Q9QZR5

Annotation

Keyword

ATP-binding
Alternative splicing
Apoptosis
Cytoplasm
DNA damage
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Transcription regulation
Tumor suppressor
Ubl conjugation

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
nucleus
cytoplasm
protein-containing complex
cytoplasmic stress granule
PML body
RNA polymerase II transcription regulator complex
nuclear body

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 36 in total

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GO Term
lung morphogenesis
gene expression
respiratory system process
cell population proliferation
positive regulation of cell population proliferation
positive regulation of angiogenesis
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
DNA damage response, signal transduction by p53 class mediator
positive regulation of DNA binding

Displaying entries **1 - 10** of 28 in total

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GO Term
3-phosphoinositide-dependent protein kinase activity
eukaryotic translation initiation factor 2alpha kinase activity
ribosomal protein S6 kinase activity
histone H3S10 kinase activity
histone H3T11 kinase activity
histone H3T6 kinase activity
histone H3S28 kinase activity
histone H2AS1 kinase activity
Rho-dependent protein serine/threonine kinase activity
transcription corepressor activity

Annotation information from UniProt.

Sequence

MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKVEPSSNWDMTGYGSHSKVYSQSKNIPPSQPASTTVSTSLPIPNPSLPYEQTIIFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLVEKADRREFIDLLKKMLTIDADKRVTPIETLNHPFVTMTHLLDFPHSAHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNNQLTTVHNQAPTTSSATLSLANPEVSILNYQSALYQPSAASMAAVAPRSMPLQTGTAQICARPDPFQQALIVCPPGFQGLQASPSKHAGYSVRMENAVPIVTQAPGAQPLQIQPGLLAQQAWPGGAQQILLPPAWQQLTGVATHTSVQHAAVIPETMAGTQQLADWRNTHAHGSHYNPIMQQPALLTGHVTLPAAQPLNVGVAHVMRQQPTSTTSSRKSKQHQSSVRNVSTCEVTSSQAISSPQRSKRVKENTPPRCAMVHSSPACSTSVTCGWGDVASSTTRERQRQTIVIPDTPSPTVSVITISSDTDEEEEQKHAPTSTVSKQRKNVISCVTVHDSPYSDSSSNTSPYSVQQRTGHNGTNTLDTKGGLENHCTGNPRTIIVPPLKTQASEVLVECDSLGPAISASHHSSSFKSKSSSTVTSTSGHSSGSSSGAIAYRQQRPGPHFQQQQPLNLSQAQQHMAADRTGSHRRQQAYITPTMAQAPYTFPHNSPSHGTVHPHLAAAAHLPTQPHLYTYTAPTALGSTGTVAHLVASQGSARHTVQHTAYPASIVHQVPVSMGPRVLPSPTIHPSQYPAQFAHQTYISASPASTVYTGYPLSPAKVNQYPYI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
884		GlyGen
1009	G49108TO	GlyGen The O-GlcNAc Database
1066		GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Mus musculus
Regulation of MECP2 expression and activity	Mus musculus
Regulation of TP53 Activity through Phosphorylation	Mus musculus
SUMOylation of transcription cofactors	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

Annotation

International Collaboration

Acknowledgements