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Interleukin-12 subunit alpha

Summary

UniProt ID

Q9R103

Gene Symbol

Il12a

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q9R103

Annotation

Keyword

Cytokine
Disulfide bond
Glycoprotein
Growth factor
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 33 in total

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GO Term
positive regulation of T cell mediated cytotoxicity
immune response
cell population proliferation
cell migration
positive regulation of natural killer cell activation
T cell proliferation
negative regulation of interleukin-17 production
positive regulation of type II interferon production
positive regulation of mononuclear cell proliferation
positive regulation of smooth muscle cell apoptotic process

Displaying **all 4** entries
GO Term
interleukin-12 complex
cell surface
extracellular space
cytoplasm

Displaying **all 6** entries
GO Term
interleukin-27 binding
protein heterodimerization activity
cytokine activity
interleukin-12 receptor binding
growth factor activity
interleukin-12 beta subunit binding

Annotation information from UniProt.

Sequence

MCQSRYLLFLATLVLLNHLTSARVIPVSGPAKCLNQSQNLLKTTDDMVRTAREKLKHYSCTAGDIDHEDITRDKTSTLEACLPLELHKNESCLATKETSSIIRGSCLPPQKTSLMMTLCLGSIYEDLKMYQSEFQAINAALQSHNHQQITLDRNMLMAIDELMRSLNHSGETLHQKAPMGEADPYRVKMKLCILLHAFSTRVMTINRVMNYLSSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites