Cubilin

Summary
UniProt ID
Q9TU53
Gene Symbol
  • CUBN
Organism
Canis lupus familiaris (dog)
External Links
Annotation
Keyword
  • Calcium
  • Cell membrane
  • Cholesterol metabolism
  • Cleavage on pair of basic residues
  • Coated pit
  • Cobalamin
  • Direct protein sequencing
  • Disulfide bond
  • EGF-like domain
  • Endosome
  • Glycoprotein
  • Lysosome
  • Metal-binding
  • Phosphoprotein
  • Protein transport
  • Reference proteome
  • Repeat
  • Signal
Gene Ontology (GO)
Sequence
MSSPFLWSLIILLTFAESNGEAGGFELQRQKRSIDFQQPRMATERGNLVFLVGSAQNIEFRTGSLGKIKLNEEDLGECLHQIQKNKEDITDLKRSAVNVPQNISSQIHQLNSKLVDLERKFQSLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPSQWKGPLCSVDVNECQIYSGTPLGCQNGATCENTAGSYSCLCSPETHGPQCASKYDDCEGGSKALCVHGICEDLVRVKADEPKYNCICDAGWTSPLNSSACVLDIDECNLQHAPCSPLVQCFNTQGSFYCGACPTGWQGNGYSCQDIDECKINNGGCSVVPPVMCVNTLGSYHCQACPPGYQGDGRVCTVIDICSVNNGGCHPEASCSSVLGSLPLCTCLPGYTGNGYGPNGCAQLSDTCLSHPCLNGQCIETVSGYLCKCESGWAGINCTENINECLSNPCFNGGTCVDGVNAFSCECTRFWTGFLCQIPQQVCGGSLSGMDGSFSYMSPDVGYVHDVNCFWVIRTEDRKVLRITFTFFQLESVNNCPHEFLQIHDGDSSAALQLGRFCGSVLPHELLSSNNALYFHLYSEHFRSGRGFTIRWETQQPECGGILMGTYGSIKSPGYPGNYPPGRDCVWQVVTSPDLLITFTFGTLSLEHHDDCSKDYLEIRDGPLYQDPSLGKFCTTLSVPPLQTTGPFARVHFHSDNQINDQGFHITYLTSPSDLHCGGNYTDPEGLLSSDLSGPFTHNRQCIYIIKQPLGEQIQVNFTHVELEGQSSCSQSHIEVRDDKILLGKVCDNETLPHIKSIRNHIWIRLKIDASLVRASFRAVYQVACGGELTGEGVIRSPFYPNVYPGERICRWTIHQPQSQVVILNFTAFGIESSAHCDTDYIEIGSSSILGSPENKKYCGTDIPLFITSVYNFLYVIFVKSSSTENHGFMAKFSAADLACGEILTESTGIIQSPGHPNIYPHGINCTWHILVQPGHLIHLIFRKFHLEFHYNCTNDYLEVYDTGSNTYLGRYCGKSIPPSLTSSTNSLKLIFVADSDLAYEGFLINYEATDASSACMEDYTENSGTFTSPNFPNNYPNNWKCIYRITVETSQQIALHFTNFALEEAIGGQCVADFVEIRDGGYETSPPLGTYCGSIPPPRIISHSNKLWLQFTSDFLGSGPGFSAYWDGSLTGCGGNITTPTGVFTSPSYPMPYYHSSECYWLLKASHGSPFELEFEDFHLEHHPNCTLDYLAVYDGPSTSSHLLSQLCGNEKPPVIRSTGDSMFLKFRTDEDQQGGGFLAKYQQTCRNVVIVNRNYGILESIHYPNPYSDNQRCNWTIQATTGNTVNYTFLAFELENHINCSTDYLELYDGPRRMGRYCGADMPPTGSTTGSKLQVLFYTDGVGHQEKGFQMQWFIHGCGGELSGTTGSFSSPGYPNTYPPNKECIWYITTAPGSSIQLTIHDFDVEYHARCNFDVLEVYGGPDFHSPRITQLCSQRSSENPMQVSSTGNELAIRFKTDSSINGRGFNASWQAVPGGCGGIFQAPNGEIHSPNYPSPYRGNTDCSWVIRVERNHRILLNFTDFDLEPQDSCITAYDGLSSTTTRLASVCGRQQLTNPITSSGNSLFLRFQSGPSRQGRGFRAQFNQVCGGHILTNSFDTISSPLFPAKYPNNQNCSWVIQAQPPFNHITLSFDHFGLESSTTCTQDFLEILDGDYDDAPLRGRYCGHSMPHPITSFSSALTLRFVSDSRVNSDGFHATYAASSSACGGTFHMAEGIFNSPGYPEVYPSNVECVWNIVSSPGNRLQLSFITFQLEDSQDCSRDFVEVREGNATGHLVGRYCGNVLPLNYSSIVGHILWIRFVSDGSGSGTGFQATFTKIFGNDNIVGTHGKIASPLWPGRYPHNSNYQWIVNVNATQVIHGRILEIDIEGAQSCYYDKLRVYDGLGIHSRLIGTYCGTQTTSFSSSRNSLTFQFSSDSSITGKGFLLEWFAVNASGGPLPTIATGACGGFLRTGDAPVFLFSPGWPESYSNSADCTWLIQAPDSTVELNILSLDIEAQRTCDYDKLVIRDGDSNLAPQLAVLCGREIPGPIRSTGEYMFIRFTSDFSITGAGFNASFHKSCGGYLHADRGIITSPQYPETYSPNLNCSWHVLVQSGLTIAVHFEQPFQIPSGDSSCSQGDYLVLKNGPDIYSPPLGPYGRNGHFCGSRPSSTLFTSDNQMFVQFISDGSNGGQGFKIKYEAKSLACGGNIYIHDVNSAGYVTSPGHPNNYPQHADCNWLIAAPPGKLIRVQFEDQFNIEETPNCVSNYLELRDGVDSNAPLLAKLCGRSLPSSQLSSGEVMYLRFRSDNSSTQVGFKIKYAIAQCGGRVTGQSGIIESSGYPTLPYRDNSFCEWHLKGPSGHYLTIHFEDFHLQNSSGCEKDFVEIWENHTSGNLLGRYCGNTIPDSIDTSSNVALVRFVTDGSVTASGFRLRFESSMEACGGELQGPTGTFTSPNYPNPNPHGRVCEWRIMVQEGRRITLTFNNLRLEAHPSCYSEHVTIFNGIRNNSPQLEKLCGSVNASSEIKSSGNTMKVVFFTDGSRPFGGFSATYTSSEDAVCGGSLTHFPEGNFTSPGYNGVSNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFRVGNADGPLMWRLCGPSKPIVPLVIPYPEVWIHFVTNEHVEHVGFHAEYSFTDCGGIQLGESGVIASPNYPASYDSLTHCSWLLEAPQGFTITLTFSDFDIEDHATCAWDSVSVRNGGSPGSPIIGQYCGTSNPRTIQSGSNQLVVIFNSDHSVQNGGFYATWNTQTLGCGGILHSDNGTIRSPHWPQNFPENSRCSWTVITHESKQLEISFDNNFRIPSGDGQCQNSFVKVWAGTEEVAESLLATGCGNVAPGSILTPRNVFIAVFQSQETPAQGFSASFVSRCGGNFTNPSGYILSPNYPRQYDNNMNCTYIIEADPLSVVLLTFESFHLEARSAITGSCANDGVHIIRGSNLSSTPFATVCGNEILSPVTILGPVLLNFYSNAHTTDLGFKFNYKITSCGGVFNVSTGVIKSPAYSYSDYPNNIYCLYTIVGRDDRVVQLKFSDFDVVPSTFCSQDYLAIYDGSNISDPLLGKFCGSNLPPNIKSSNHSMLLVFKTDSFQTARGWKITFQQTLGPQQGCGGYLTGSDNTFASPDSDSNGRYDKNLNCVWFIIAPVNKLIKLTFNTFALEAQSAMQRCIYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFVSDVTLEREGFNATYTTVDMPCGGTYNATWTPQSISSPNSSNPEVPLSMCMWFLEAPPHQQVKITVWALELHSQDCDQNYLEFRDSPESNGSPGPQICGRNASATPTFYSSRSTAIVIFKSEVLNRNSRVGFTYQIAGCNREYNKAFGNLKSPGWPDNYDNNLDCTVILTAPQNHTISLFFHSFGIEDSSECTHDFLEVRNGSDSSSPLFGTYCGTLLPDPIFSRNNKLYLRFKTDSATSNRGYEIVWTSSPSGCGGTLYGDSGSFTSPGYPGTYPNNTDCEWAIIAPAGRPVTVTFYFISIDDPGDCVQNYLILYDGPDANSPSFGPYCGADTNIAPFVASSHRVFIKFHAEYAVYPSAIRLTWDS
Glycosylation Sites
Displaying entries 21 - 30 of 44 in total
Position Description PubMed ID GlyTouCan ID Source
1961 N-linked (GlcNAc...) asparagine
2082 N-linked (GlcNAc...) asparagine
2114 N-linked (GlcNAc...) asparagine
2317 N-linked (GlcNAc...) asparagine
2383 N-linked (GlcNAc...) asparagine
2397 N-linked (GlcNAc...) asparagine
2528 N-linked (GlcNAc...) asparagine
2578 N-linked (GlcNAc...) asparagine
2589 N-linked (GlcNAc...) asparagine
2607 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024