GlyCosmos Portal

Submissions

F-box/LRR-repeat protein 2

Summary

UniProt ID

Q9UKC9

Gene Symbol

FBL2
FBL3
FBXL2

Gene ID

25827

Organism

Homo sapiens (human)

External Links

GlyGen: Q9UKC9
Re-Glyco: Q9UKC9

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Calmodulin-binding
Host-virus interaction
Isopeptide bond
Leucine-rich repeat
Membrane
Phosphoprotein
Prenylation
Proteomics identification
Reference proteome
Repeat
Ubl conjugation
Ubl conjugation pathway

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
cytoplasm
membrane
SCF ubiquitin ligase complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 10** entries
GO Term
negative regulation of NLRP3 inflammasome complex assembly
protein ubiquitination
protein monoubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
proteolysis
protein modification process
regulation of inflammatory response
regulation of autophagy
modulation by host of viral RNA genome replication

Displaying **all 4** entries
GO Term
phosphatidylinositol 3-kinase regulatory subunit binding
calmodulin binding
protein phosphatase binding
ubiquitin ligase-substrate adaptor activity

Annotation information from UniProt.

Sequence

MVFSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQTDVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCVIL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites