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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Dermatan-sulfate epimerase
Summary
- UniProt ID
- Q9UL01
- Gene Symbol
-
- DSE
- SART2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cytoplasmic vesicle
- Disease variant
- Ehlers-Danlos syndrome
- Glycoprotein
- Golgi apparatus
- Isomerase
- Manganese
- Metal-binding
- Microsome
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| Golgi apparatus |
| cytoplasmic vesicle membrane |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| metal ion binding |
| chondroitin-glucuronate 5-epimerase activity |
Sequence
MRTHTRGAPSVFFIYLLCFVSAYITDENPEVMIPFTNANYDSHPMLYFSRAEVAELQLRAASSHEHIAARLTEAVHTMLSSPLEYLPPWDPKDYSARWNEIFGNNLGALAMFCVLYPENIEARDMAKDYMERMAAQPSWLVKDAPWDEVPLAHSLVGFATAYDFLYNYLSKTQQEKFLEVIANASGYMYETSYRRGWGFQYLHNHQPTNCMALLTGSLVLMNQGYLQEAYLWTKQVLTIMEKSLVLLREVTDGSLYEGVAYGSYTTRSLFQYMFLVQRHFNINHFGHPWLKQHFAFMYRTILPGFQRTVAIADSNYNWFYGPESQLVFLDKFVMRNGSGNWLADQIRRNRVVEGPGTPSKGQRWCTLHTEFLWYDGSLKSVPPPDFGTPTLHYFEDWGVVTYGSALPAEINRSFLSFKSGKLGGRAIYDIVHRNKYKDWIKGWRNFNAGHEHPDQNSFTFAPNGVPFITEALYGPKYTFFNNVLMFSPAVSKSCFSPWVGQVTEDCSSKWSKYKHDLAASCQGRVVAAEEKNGVVFIRGEGVGAYNPQLNLKNVQRNLILLHPQLLLLVDQIHLGEESPLETAASFFHNVDVPFEETVVDGVHGAFIRQRDGLYKMYWMDDTGYSEKATFASVTYPRGYPYNGTNYVNVTMHLRSPITRAAYLFIGPSIDVQSFTVHGDSQQLDVFIATSKHAYATYLWTGEATGQSAFAQVIADRHKILFDRNSAIKSSIVPEVKDYAAIVEQNLQHFKPVFQLLEKQILSRVRNTASFRKTAERLLRFSDKRQTEEAIDRIFAISQQQQQQSKSKKNRRAGKRYKFVDAVPDIFAQIEVNEKKIRQKAQILAQKELPIDEDEEMKDLLDFADVTYEKHKNGGLIKGRFGQARMVTTTHSRAPSLSASYTRLFLILNIAIFFVMLAMQLTYFQRAQSLHGQRCLYAVLLIDSCILLWLYSSCSQSQC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 183 | N-linked (GlcNAc...) (complex) asparagine |
|
||
| 336 | N-linked (GlcNAc...) (high mannose) asparagine | |||
| 338 |
|
|||
| 411 | N-linked (GlcNAc...) (complex) asparagine |
|
||
| 642 | N-linked (GlcNAc...) (complex) asparagine |
|
||
| 648 | N-linked (GlcNAc...) (paucimannose) asparagine |
|
G90659AW
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Dermatan sulfate biosynthesis | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060320 | inguinal hernia | |
| DOID:0110106 | atrial heart septal defect 1 | |
| DOID:0110107 | atrial heart septal defect 2 | |
| DOID:0110108 | atrial heart septal defect 3 | |
| DOID:0110109 | atrial heart septal defect 4 | |
| DOID:0110110 | atrial heart septal defect 5 | |
| DOID:0110111 | atrial heart septal defect 6 | |
| DOID:0110112 | atrial heart septal defect 7 | |
| DOID:0110113 | atrial heart septal defect 8 | |
| DOID:0110114 | atrial heart septal defect 9 |
