Matrix metalloproteinase-17

Summary
UniProt ID
Q9ULZ9
Gene Symbol
  • MMP17
  • MT4MMP
Organism
Homo sapiens (human)
External Links
GlyGen
Q9ULZ9
PubChem
Q9ULZ9
The Human Metabolome Database
HMDBP07806
Annotation
Keyword
  • Alternative splicing
  • Calcium
  • Cell membrane
  • Cleavage on pair of basic residues
  • Disulfide bond
  • Extracellular matrix
  • GPI-anchor
  • Metal-binding
  • Metalloprotease
  • Reference proteome
  • Repeat
  • Signal
  • Zinc
  • Zymogen
Gene Ontology (GO)
Sequence
MRRRAARGPGPPPPGPGLSRLPLPLLLLLALGTRGGCAAPAPAPRAEDLSLGVEWLSRFGYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFSLPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQSPLWRGVPSTLDDAMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTARDWLVCGDSQADGSVAAGVDAAEGPRAPPGQHDQSRSEDGYEVCSCTSGASSPPGAPGPLVAATMLLLLPPLSPGALWTAAQALTL
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
137 N-linked (GlcNAc...) asparagine
318 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Activation of Matrix Metalloproteinases Homo sapiens
Disease
Displaying entries 1 - 10 of 23 in total
DO ID Disease Name Source
DOID:11476 osteoporosis
DOID:11934 head and neck cancer
DOID:1612 breast cancer
DOID:162 cancer
DOID:1936 atherosclerosis
DOID:2348 arteriosclerotic cardiovascular disease
DOID:2349 arteriosclerosis
DOID:299 adenocarcinoma
DOID:3393 coronary artery disease
DOID:3458 breast adenocarcinoma

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024