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MIRAGE
Frizzled-2
Summary
- UniProt ID
- Q9VVX3
- Gene Symbol
-
- CG9739
- fz2
- Gene ID
- 40090
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- Cell membrane
- Developmental protein
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| plasma membrane |
| membrane |
| Wnt signalosome |
| Wnt-Frizzled-LRP5/6 complex |
| GO Term |
|---|
| Wnt receptor activity |
| G protein-coupled receptor activity |
| PDZ domain binding |
| Wnt-protein binding |
Sequence
MRHNRLKVLILGLVLLLTSCRADGPLHSADHGMGGMGMGGHGLDASPAPGYGVPVIPKDPNLRCEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGAPDRTGANQALIKQRPPIPHPYAGSGMGMPVGSAAGSLLATPYTQAGGASVASTSHHHLHHHVLKQPAASHV
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Assembly of receptor complex | Drosophila melanogaster |
| Asymmetric localization of PCP proteins | Drosophila melanogaster |
| Ca2+ pathway | Drosophila melanogaster |
| Phosphorylation of ARR | Drosophila melanogaster |
| Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM | Drosophila melanogaster |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | Drosophila melanogaster |
