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Standards Ontologies Notations
Heparanase

Summary
UniProt ID
Q9Y251
Gene Symbol
  • HPSE
  • HEP
  • HPA
  • HPA1
  • HPR1
  • HPSE1
  • HSE1
Organism
Homo sapiens (human)
External Links
GlyGen
Q9Y251
PubChem
Q9Y251
The Human Metabolome Database
HMDBP02807
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Calcium
  • Cell adhesion
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Hydrolase
  • Lysosome
  • Magnesium
  • Membrane
  • Nucleus
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Annotation information from UniProt.
Sequence
MLLRSKPALPPPLMLLLLGPLGPLSPGALPRPAQAQDVVDLDFFTQEPLHLVSPSFLSVTIDANLATDPRFLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPKKESTFEERSYWQSQVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLYTFANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADIFINGSQLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYLNGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAPLLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKLVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYLRLPYPFSNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYSFFVIRNAKVAACI
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 7 entries
Position Description PubMed ID GlyTouCan ID Source
162 N-linked (GlcNAc...) asparagine
178 N-linked (GlcNAc...) asparagine
200 N-linked (GlcNAc...) asparagine
217 N-linked (GlcNAc...) asparagine
238 N-linked (GlcNAc...) asparagine
456
459 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
HS-GAG degradation Homo sapiens
Neutrophil degranulation Homo sapiens
Disease
Displaying entries 191 - 200 of 414 in total
DO ID Disease Name Source
DOID:1781 thyroid cancer
DOID:1790 malignant mesothelioma
DOID:1793 pancreatic cancer
DOID:1800 neuroendocrine carcinoma
DOID:1837 diabetic ketoacidosis
DOID:1856 cherubism
DOID:1883 hepatitis C
DOID:1909 melanoma
DOID:1936 atherosclerosis
DOID:2021 placenta cancer
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024