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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Type 2 lactosamine alpha-2,3-sialyltransferase
Summary
- UniProt ID
- Q9Y274
- Gene Symbol
-
- ST3GAL6
- SIAT10
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0012688
- GlyConnect
- GlyGen
- Q9Y274
- PubChem
- Q9Y274
- The Human Metabolome Database
- HMDBP00773
Annotation
- Keyword
-
- Alternative splicing
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| membrane |
| extracellular exosome |
| GO Term |
|---|
| beta-galactoside alpha-2,3-sialyltransferase activity |
| sialyltransferase activity |
| beta-galactoside (CMP) alpha-2,3-sialyltransferase activity |
Sequence
MRGYLVAIFLSAVFLYYVLHCILWGTNVYWVAPVEMKRRNKIQPCLSKPAFASLLRFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKLQSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFKYNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLTQD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 129 | N-linked (GlcNAc...) asparagine |
|
||
| 181 | N-linked (GlcNAc...) asparagine |
|
||
| 282 | N-linked (GlcNAc...) asparagine |
|
||
| 295 | N-linked (GlcNAc...) asparagine | |||
| 304 |
|
|
||
| 308 | N-linked (GlcNAc...) asparagine | |||
| 327 | N-linked (GlcNAc...) asparagine |
G83460ZZ
G95133RI
G86795LJ
G52527GH
G24954UD
G02030ZB
G00912UN
G99966GV
G80223IX
G51640FO
G20210JR
G01650EU
G80920RR
G84820NF
G64527OM
G95865ZB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Keratan sulfate biosynthesis | Homo sapiens |
| Lewis blood group biosynthesis | Homo sapiens |
| Pre-NOTCH Processing in Golgi | Homo sapiens |
| Sialic acid metabolism | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080199 | colorectal carcinoma | |
| DOID:10534 | stomach cancer | |
| DOID:162 | cancer | |
| DOID:305 | carcinoma | |
| DOID:3571 | liver cancer | |
| DOID:4015 | sarcomatoid carcinoma | |
| DOID:5672 | large intestine cancer | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:9256 | colorectal cancer | |
| DOID:9538 | multiple myeloma |
