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Repository for lectin-assisted multimodality data
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MIRAGE
Atrial natriuretic peptide-converting enzyme
Summary
- UniProt ID
- Q9Y5Q5
- Gene Symbol
-
- CORIN
- CRN
- TMPRSS10
- Gene ID
- 10699
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Autocatalytic cleavage
- Cardiomyopathy
- Cell membrane
- Disulfide bond
- Glycoprotein
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal-anchor
- Transmembrane helix
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| nuclear body |
| extracellular region |
| plasma membrane |
| actin cytoskeleton |
| cell surface |
| GO Term |
|---|
| endopeptidase activity |
| serine-type endopeptidase activity |
Sequence
MKQSPALAPEERCRRAGSPKPVLRADDNNMGNGCSQKLATANLLRFLLLVLIPCICALVLLLVILLSYVGTLQKVYFKSNGSEPLVTDGEIQGSDVILTNTIYNQSTVVSTAHPDQHVPAWTTDASLPGDQSHRNTSACMNITHSQCQMLPYHATLTPLLSVVRNMEMEKFLKFFTYLHRLSCYQHIMLFGCTLAFPECIIDGDDSHGLLPCRSFCEAAKEGCESVLGMVNYSWPDFLRCSQFRNQTESSNVSRICFSPQQENGKQLLCGRGENFLCASGICIPGKLQCNGYNDCDDWSDEAHCNCSENLFHCHTGKCLNYSLVCDGYDDCGDLSDEQNCDCNPTTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNCSCHSQGLVECRNGQCIPSTFQCDGDEDCKDGSDEENCSVIQTSCQEGDQRCLYNPCLDSCGGSSLCDPNNSLNNCSQCEPITLELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMFFSCTILVPKCDVNTGEHIPPCRALCEHSKERCESVLGIVGLQWPEDTDCSQFPEENSDNQTCLMPDEYVEECSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKERDLWECPSNKQCLKHTVICDGFPDCPDYMDEKNCSFCQDDELECANHACVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSFLMVHRAATEHHVCADGWQEILSQLACKQMGLGEPSVTKLIQEQEKEPRWLTLHSNWESLNGTTLHELLVNGQSCESRSKISLLCTKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVRPVCLPNPEQWLEPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEHCQSYFDMKTITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVEWIKRQIYIQTFLLN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 80 | N-linked (GlcNAc...) asparagine |
|
||
| 104 | N-linked (GlcNAc...) asparagine |
|
||
| 135 | N-linked (GlcNAc...) asparagine |
|
||
| 141 | N-linked (GlcNAc...) asparagine |
|
||
| 231 | N-linked (GlcNAc...) asparagine |
|
||
| 245 | N-linked (GlcNAc...) asparagine |
|
||
| 251 | N-linked (GlcNAc...) asparagine |
|
||
| 305 | N-linked (GlcNAc...) asparagine |
|
||
| 320 | N-linked (GlcNAc...) asparagine |
|
||
| 376 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Physiological factors | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080326 | familial hypertrophic cardiomyopathy | |
| DOID:10591 | pre-eclampsia | |
| DOID:10763 | hypertension |
