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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Mitotic spindle assembly checkpoint protein MAD2A
Summary
- UniProt ID
- Q9Z1B5
- Gene Symbol
-
- Mad2l1
- Mad2a
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Centromere
- Chromosome
- Cytoskeleton
- Kinetochore
- Mitosis
- Nucleus
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| nucleoplasm |
| mitotic checkpoint complex |
| perinuclear region of cytoplasm |
| nucleus |
| chromosome |
| cytoplasm |
| mitotic spindle |
| mitotic spindle assembly checkpoint MAD1-MAD2 complex |
| nuclear pore nuclear basket |
| cytosol |
| GO Term |
|---|
| protein homodimerization activity |
Sequence
MAQQLAREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLTTTDPELIKYLNNVVEQLKEWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKEEGVRREKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNCEEVRLRSFTTTIHKVNSMVAYKTPVND
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| APC-Cdc20 mediated degradation of Nek2A | Mus musculus |
| APC/C:Cdc20 mediated degradation of mitotic proteins | Mus musculus |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | Mus musculus |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | Mus musculus |
| EML4 and NUDC in mitotic spindle formation | Mus musculus |
| Inactivation of APC/C via direct inhibition of the APC/C complex | Mus musculus |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | Mus musculus |
| Mitotic Prometaphase | Mus musculus |
| RHO GTPases Activate Formins | Mus musculus |
| Resolution of Sister Chromatid Cohesion | Mus musculus |
