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Insulin-like growth factor-binding protein 3

Summary

UniProt ID

P17936

Gene Symbol

IGFBP3
IBP3

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011577

GlyConnect

1945

GlyGen

P17936

PubChem

P17936

The O-GlcNAc Database

P17936

Annotation

Keyword

3D-structure
Alternative splicing
Apoptosis
Direct protein sequencing
Disulfide bond
Glycoprotein
Growth factor binding
Phosphoprotein
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 17 in total

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GO Term
regulation of cell growth
protein phosphorylation
apoptotic process
negative regulation of cell population proliferation
negative regulation of signal transduction
regulation of glucose metabolic process
negative regulation of smooth muscle cell migration
positive regulation of apoptotic process
type B pancreatic cell proliferation
positive regulation of myoblast differentiation

Displaying **all 6** entries
GO Term
endoplasmic reticulum lumen
insulin-like growth factor ternary complex
extracellular region
extracellular space
nucleus
insulin-like growth factor binding protein complex

Displaying **all 6** entries
GO Term
fibronectin binding
insulin-like growth factor binding
protein tyrosine phosphatase activator activity
metal ion binding
insulin-like growth factor I binding
insulin-like growth factor II binding

Annotation information from UniProt.

Sequence

MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
116		23586699 24498956
199		23586699

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Post-translational protein phosphorylation	Homo sapiens
Regulation of IGF Activity by IGFBP	Homo sapiens
TP53 Regulates Transcription of Death Receptors and Ligands	Homo sapiens