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Low-density lipoprotein receptor

Summary

UniProt ID

P35951

Gene Symbol

Ldlr

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003602
GlyGen: P35951
PubChem: P35951
The O-GlcNAc Database: P35951

Annotation

Keyword

Cell membrane
Cholesterol metabolism
Coated pit
Disulfide bond
EGF-like domain
Endocytosis
Endosome
Glycoprotein
Golgi apparatus
LDL
Lipid transport
Lysosome
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 39 in total

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GO Term
lipid metabolic process
endocytosis
phagocytosis
positive regulation of gene expression
negative regulation of gene expression
positive regulation of inflammatory response
regulation of protein metabolic process
establishment of localization in cell
lipoprotein metabolic process
lipoprotein catabolic process

Displaying entries **1 - 10** of 19 in total

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GO Term
extracellular space
lysosome
Golgi apparatus
plasma membrane
somatodendritic compartment
receptor complex
recycling endosome membrane
PCSK9-LDLR complex
basolateral plasma membrane
apical part of cell

Displaying **all 8** entries
GO Term
amyloid-beta binding
low-density lipoprotein particle receptor activity
lipoprotein particle binding
very-low-density lipoprotein particle receptor activity
identical protein binding
protease binding
calcium ion binding
low-density lipoprotein particle binding

Annotation information from UniProt.

Sequence

MSTADLMRRWVIALLLAAAGVAAEDSCSRNEFQCRDGKCIASKWVCDGSPECPDGSDESPETCMSVTCQSNQFSCGGRVSRCIPDSWRCDGQVDCENDSDEQGCPPKTCSQDDFRCQDGKCISPQFVCDGDRDCLDGSDEAHCQATTCGPAHFRCNSSICIPSLWACDGDVDCVDGSDEWPQNCQGRDTASKGVSSPCSSLEFHCGSSECIHRSWVCDGEADCKDKSDEEHCAVATCRPDEFQCADGSCIHGSRQCDREHDCKDMSDELGCVNVTQCDGPNKFKCHSGECISLDKVCDSARDCQDWSDEPIKECKTNECLDNNGGCSHICKDLKIGSECLCPSGFRLVDLHRCEDIDECQEPDTCSQLCVNLEGSYKCECQAGFHMDPHTRVCKAVGSIGYLLFTNRHEVRKMTLDRSEYTSLLPNLKNVVALDTEVTNNRIYWSDLSQKKIYSALMDQAPNLSYDTIISEDLHAPDGLAVDWIHRNIYWTDSVPGSVSVADTKGVKRRTLFQEAGSRPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIHSLVTENIQWPNGITLDLSSGRLYWVDSKLHSISSIDVNGGNRKTILEDENRLAHPFSLAIYEDKVYWTDVINEAIFSANRLTGSDVNLVAENLLSPEDIVLFHKVTQPRGVNWCETTALLPNGGCQYLCLPAPQIGPHSPKFTCACPDGMLLAKDMRSCLTEVDTVLTTQGTSAVRPVVTASATRPPKHSEDLSAPSTPRQPVDTPGLSTVASVTVSHQVQGDMAGRGNEEQPHGMRFLSIFFPIALVALLVLGAVLLWRNWRLKNINSINFDNPVYQKTTEDELHICRSQDGYTYPSRQMVSLEDDVA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
273

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Mus musculus
Chylomicron clearance	Mus musculus
Clathrin-mediated endocytosis	Mus musculus
LDL clearance	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements