GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs ▲	GO Labels	GO IDs
Transcription factor SOX-13	Q04891	Sox13	Sox-13	Sox13 Sox-13	Mus musculus	10090	1	1	DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding cell fate commitment cytoplasm gamma-delta T cell differentiation identical protein binding negative regulation of DNA-templated transcription negative regulation of canonical Wnt signaling pathway negative regulation of transcription by RNA polymerase II nucleoplasm nucleus positive regulation of brown fat cell differentiation positive regulation of gamma-delta T cell differentiation regulation of DNA-templated transcription regulation of gamma-delta T cell differentiation regulation of transcription by RNA polymerase II sequence-specific DNA binding spinal cord oligodendrocyte cell differentiation transcription cis-regulatory region binding	GO:0000122 GO:0000976 GO:0000977 GO:0000978 GO:0000981 GO:0001217 GO:0001227 GO:0003677 GO:0005634 GO:0005654 GO:0005737 GO:0006355 GO:0006357 GO:0021529 GO:0042492 GO:0042802 GO:0043565 GO:0045165 GO:0045586 GO:0045588 GO:0045892 GO:0090090 GO:0090336
Transcription factor SOX-7	Q9BT81	SOX7		SOX7	Homo sapiens	9606		1	DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding anatomical structure morphogenesis cell differentiation chromatin cytoplasm endoderm formation negative regulation of DNA-templated transcription negative regulation of cell population proliferation nucleoplasm nucleus positive regulation of DNA-templated transcription positive regulation of cysteine-type endopeptidase activity involved in apoptotic process regulation of DNA-templated transcription regulation of canonical Wnt signaling pathway sequence-specific double-stranded DNA binding transcription cis-regulatory region binding	GO:0000785 GO:0000976 GO:0000978 GO:0000981 GO:0001706 GO:0003700 GO:0005634 GO:0005654 GO:0005737 GO:0006355 GO:0008285 GO:0009653 GO:0030154 GO:0043280 GO:0045892 GO:0045893 GO:0060828 GO:1990837
RNA polymerase-associated protein LEO1	Q8WVC0	LEO1	RDL	LEO1 RDL	Homo sapiens	9606		1	Cdc73/Paf1 complex RNA polymerase II C-terminal domain phosphoserine binding Wnt signaling pathway centrosome endodermal cell fate commitment fibrillar center mRNA polyadenylation negative regulation of myeloid cell differentiation nucleoplasm nucleus positive regulation of mRNA 3'-end processing positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II stem cell population maintenance transcription elongation by RNA polymerase II	GO:0001650 GO:0001711 GO:0005634 GO:0005654 GO:0005813 GO:0006368 GO:0006378 GO:0016055 GO:0016593 GO:0019827 GO:0031442 GO:0032968 GO:0045638 GO:0045944 GO:1990269
Keratin, type I cytoskeletal 18	P05784	Krt18	Kerd Krt1-18	Krt18 Kerd Krt1-18	Mus musculus	10090	4	1	Golgi to plasma membrane protein transport cell periphery centriolar satellite cytoplasm cytoskeleton cytosol external side of plasma membrane extracellular space extrinsic apoptotic signaling pathway hepatocyte apoptotic process intermediate filament intermediate filament cytoskeleton organization keratin filament microtubule organizing center negative regulation of apoptotic process nuclear matrix nucleolus perinuclear region of cytoplasm protein-containing complex scaffold protein binding structural molecule activity tumor necrosis factor-mediated signaling pathway	GO:0005198 GO:0005615 GO:0005730 GO:0005737 GO:0005815 GO:0005829 GO:0005856 GO:0005882 GO:0009897 GO:0016363 GO:0032991 GO:0033209 GO:0034451 GO:0043001 GO:0043066 GO:0045095 GO:0045104 GO:0048471 GO:0071944 GO:0097110 GO:0097191 GO:0097284
Alanyl-tRNA editing protein Aarsd1	Q9BTE6	AARSD1		AARSD1	Homo sapiens	9606		1	ATP binding Ser-tRNA(Ala) hydrolase activity alanine-tRNA ligase activity alanyl-tRNA aminoacylation cytoplasm metal ion binding nucleic acid binding nucleus regulation of translational fidelity	GO:0002196 GO:0003676 GO:0004813 GO:0005524 GO:0005634 GO:0005737 GO:0006419 GO:0006450 GO:0046872
Methyltransferase	M8AQW9	TRIUR3_34803		TRIUR3_34803	Triticum urartu	4572		1	S-adenosylmethionine-dependent methyltransferase activity membrane methylation	GO:0008757 GO:0016020 GO:0032259
Odontogenic ameloblast-associated protein	A1E959	ODAM	APIN	ODAM APIN	Homo sapiens	9606	12	1	biomineral tissue development cell periphery cytoplasm cytosol extracellular region extracellular space inflammatory response mitotic spindle nucleoplasm nucleus odontogenesis of dentin-containing tooth positive regulation of GTPase activity positive regulation of epithelial cell proliferation involved in wound healing positive regulation of gene expression positive regulation of protein phosphorylation regulation of actin cytoskeleton organization supramolecular fiber	GO:0001934 GO:0005576 GO:0005615 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006954 GO:0010628 GO:0031214 GO:0032956 GO:0042475 GO:0043547 GO:0060054 GO:0071944 GO:0072686 GO:0099512
CCR4-NOT transcription complex subunit 1	Q6ZQ08	Cnot1	Kiaa1007	Cnot1 Kiaa1007	Mus musculus	10090	12	1	CCR4-NOT complex CCR4-NOT core complex P-body armadillo repeat domain binding cytosol miRNA-mediated post-transcriptional gene silencing molecular adaptor activity negative regulation of intracellular estrogen receptor signaling pathway negative regulation of retinoic acid receptor signaling pathway negative regulation of transcription by RNA polymerase II negative regulation of translation nuclear estrogen receptor binding nuclear retinoic acid receptor binding nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nucleus poly(A)-specific ribonuclease activity positive regulation of cytoplasmic mRNA processing body assembly positive regulation of mRNA catabolic process positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay positive regulation of nuclear-transcribed mRNA poly(A) tail shortening protein domain specific binding regulation of stem cell population maintenance trophectodermal cell differentiation	GO:0000122 GO:0000288 GO:0000932 GO:0001829 GO:0004535 GO:0005634 GO:0005829 GO:0010606 GO:0017148 GO:0019904 GO:0030014 GO:0030015 GO:0030331 GO:0033147 GO:0035195 GO:0042974 GO:0048387 GO:0060090 GO:0060213 GO:0061014 GO:0070016 GO:1900153 GO:2000036
Peroxisomal membrane protein 4	Q9JJW0	Pxmp4	Pmp24	Pxmp4 Pmp24	Mus musculus	10090	1	1	ether lipid metabolic process peroxisomal membrane peroxisome	GO:0005777 GO:0005778 GO:0046485
CCR4-NOT transcription complex subunit 2	Q8C5L3	Cnot2		Cnot2	Mus musculus	10090	11	1	CCR4-NOT complex CCR4-NOT core complex P-body cytoplasm cytosol negative regulation of intracellular estrogen receptor signaling pathway negative regulation of transcription by RNA polymerase II nuclear-transcribed mRNA poly(A) tail shortening nucleoplasm plasma membrane poly(A)-specific ribonuclease activity positive regulation of cytoplasmic mRNA processing body assembly regulation of stem cell population maintenance regulatory ncRNA-mediated gene silencing transcription corepressor binding trophectodermal cell differentiation	GO:0000122 GO:0000289 GO:0000932 GO:0001222 GO:0001829 GO:0004535 GO:0005654 GO:0005737 GO:0005829 GO:0005886 GO:0010606 GO:0030014 GO:0030015 GO:0031047 GO:0033147 GO:2000036