GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name ▲	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GO Labels	GO IDs
11-beta-hydroxysteroid dehydrogenase 1	P16232	Hsd11b1	Hsd11	Hsd11b1 Hsd11	Rattus norvegicus	10116	2		11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity NADP binding apical part of cell cellular response to estradiol stimulus cortisol dehydrogenase activity endoplasmic reticulum membrane glucocorticoid biosynthetic process glucocorticoid catabolic process intracellular membrane-bounded organelle lung development mineralocorticoid metabolic process nuclear membrane protein homodimerization activity regulation of pentose-phosphate shunt response to nutrient levels steroid binding steroid catabolic process	GO:0005496 GO:0005789 GO:0006704 GO:0006706 GO:0006713 GO:0008212 GO:0030324 GO:0031667 GO:0031965 GO:0042803 GO:0043231 GO:0043456 GO:0045177 GO:0047022 GO:0050661 GO:0070524 GO:0071392 GO:0102196
11-beta-hydroxysteroid dehydrogenase 1	P28845	HSD11B1	HSD11 HSD11L SDR26C1	HSD11B1 HSD11 HSD11L SDR26C1	Homo sapiens	9606	3	2	11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity NADP binding cortisol dehydrogenase activity endoplasmic reticulum membrane intracellular membrane-bounded organelle lung development membrane protein homodimerization activity steroid binding steroid catabolic process	GO:0005496 GO:0005789 GO:0006706 GO:0016020 GO:0030324 GO:0042803 GO:0043231 GO:0047022 GO:0050661 GO:0070524 GO:0102196
11-beta-hydroxysteroid dehydrogenase 1	Q29608	HSD11B1		HSD11B1	Saimiri sciureus	9521	3		11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity cortisol dehydrogenase activity endoplasmic reticulum membrane steroid metabolic process	GO:0005789 GO:0008202 GO:0047022 GO:0070524 GO:0102196
11-beta-hydroxysteroid dehydrogenase 1	Q6R0J2	HSD11B1		HSD11B1	Mesocricetus auratus	10036	2		11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity cortisol dehydrogenase activity endoplasmic reticulum membrane steroid metabolic process	GO:0005789 GO:0008202 GO:0047022 GO:0070524 GO:0102196
11-beta-hydroxysteroid dehydrogenase 1	P50172	Hsd11b1	Hsd11	Hsd11b1 Hsd11	Mus musculus	10090	2	2	11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity NADP binding apical part of cell cortisol dehydrogenase activity endoplasmic reticulum membrane glucocorticoid biosynthetic process glucocorticoid catabolic process intracellular membrane-bounded organelle lung development mineralocorticoid metabolic process nuclear membrane protein homodimerization activity regulation of pentose-phosphate shunt steroid binding steroid catabolic process	GO:0005496 GO:0005789 GO:0006704 GO:0006706 GO:0006713 GO:0008212 GO:0030324 GO:0031965 GO:0042803 GO:0043231 GO:0043456 GO:0045177 GO:0047022 GO:0050661 GO:0070524 GO:0102196
11-beta-hydroxysteroid dehydrogenase 1	P51975	HSD11B1		HSD11B1	Ovis aries	9940	2		11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity cortisol dehydrogenase activity endoplasmic reticulum membrane steroid metabolic process	GO:0005789 GO:0008202 GO:0047022 GO:0070524 GO:0102196
11-beta-hydroxysteroid dehydrogenase 1	Q6QLL4	HSD11B1		HSD11B1	Cavia porcellus	10141	1		11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity NADP binding cortisol dehydrogenase activity endoplasmic reticulum membrane lung development protein homodimerization activity steroid metabolic process	GO:0005789 GO:0008202 GO:0030324 GO:0042803 GO:0047022 GO:0050661 GO:0070524 GO:0102196
11-beta-hydroxysteroid dehydrogenase 1	Q7M3I4	HSD11B1		HSD11B1	Oryctolagus cuniculus	9986	3		11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity cortisol dehydrogenase activity endoplasmic reticulum membrane steroid metabolic process	GO:0005789 GO:0008202 GO:0047022 GO:0070524 GO:0102196
116 kDa U5 small nuclear ribonucleoprotein component	Q15029	EFTUD2	KIAA0031 SNRP116	EFTUD2 KIAA0031 SNRP116	Homo sapiens	9606	1	1	Cajal body GTP binding GTPase activity RNA binding U2-type catalytic step 2 spliceosome U2-type precatalytic spliceosome U4/U6 x U5 tri-snRNP complex U5 snRNA binding catalytic step 2 spliceosome cellular response to xenobiotic stimulus cytosol intracellular membrane-bounded organelle mRNA splicing, via spliceosome membrane nuclear speck nucleoplasm nucleus response to cocaine translation elongation factor activity	GO:0000398 GO:0003723 GO:0003746 GO:0003924 GO:0005525 GO:0005634 GO:0005654 GO:0005829 GO:0015030 GO:0016020 GO:0016607 GO:0030623 GO:0042220 GO:0043231 GO:0046540 GO:0071005 GO:0071007 GO:0071013 GO:0071466
116 kDa U5 small nuclear ribonucleoprotein component	O08810	Eftud2	Snrp116	Eftud2 Snrp116	Mus musculus	10090		1	Cajal body GTP binding GTPase activity U2-type catalytic step 2 spliceosome U2-type precatalytic spliceosome U4/U6 x U5 tri-snRNP complex U5 snRNA binding catalytic step 2 spliceosome cytosol intracellular membrane-bounded organelle mRNA splicing, via spliceosome nuclear speck nucleoplasm nucleus translation elongation factor activity	GO:0000398 GO:0003746 GO:0003924 GO:0005525 GO:0005634 GO:0005654 GO:0005829 GO:0015030 GO:0016607 GO:0030623 GO:0043231 GO:0046540 GO:0071005 GO:0071007 GO:0071013