GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All ▲	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Protein wntless	Q95ST2	wls	evi srt	wls evi srt	Drosophila melanogaster	7227	1	Golgi apparatus Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endomembrane system endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis imaginal disc-derived wing morphogenesis intracellular protein transport multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005794 GO:0005886 GO:0006886 GO:0007367 GO:0007476 GO:0007480 GO:0008587 GO:0010008 GO:0012505 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157 GO:0099537
Protein Wnt (Fragment)	Q6LCS9	wnt-10B		wnt-10B	Mus musculus	10090	1	Wnt signaling pathway extracellular region signaling receptor binding	GO:0005102 GO:0005576 GO:0016055
Protein Wnt-1	P24257	wnt1	int-1 wnt-1	wnt1 int-1 wnt-1	Danio rerio	7955	3	brain segmentation canonical Wnt signaling pathway cell fate commitment cerebellum morphogenesis cytokine activity extracellular space fourth ventricle development frizzled binding hindbrain development midbrain-hindbrain boundary development neuron differentiation	GO:0005109 GO:0005125 GO:0005615 GO:0021587 GO:0021592 GO:0030182 GO:0030902 GO:0030917 GO:0035284 GO:0045165 GO:0060070
Protein Wnt-1	P10108	wnt1	int1	wnt1 int1	Xenopus laevis	8355	4	Wnt signaling pathway extracellular region forebrain anterior/posterior pattern specification negative regulation of DNA-templated transcription neural crest cell fate specification signaling receptor binding	GO:0005102 GO:0005576 GO:0014036 GO:0016055 GO:0021797 GO:0045892
Protein Wnt-10 (Fragment)	P31292	wnt10		wnt10	Xenopus laevis	8355	1	Wnt signaling pathway extracellular region signaling receptor binding	GO:0005102 GO:0005576 GO:0016055
Protein Wnt-10a	P43446	wnt10a	wnt-10a	wnt10a wnt-10a	Danio rerio	7955	2	canonical Wnt signaling pathway cell fate commitment cytokine activity extracellular space frizzled binding neuron differentiation odontogenesis	GO:0005109 GO:0005125 GO:0005615 GO:0030182 GO:0042476 GO:0045165 GO:0060070
Protein Wnt-10b	Q801F7	wnt10b		wnt10b	Danio rerio	7955	2	canonical Wnt signaling pathway cell fate commitment cytokine activity extracellular space frizzled binding midbrain-hindbrain boundary development neuron differentiation	GO:0005109 GO:0005125 GO:0005615 GO:0030182 GO:0030917 GO:0045165 GO:0060070
Protein Wnt-11	O73864	wnt11	wnt-11	wnt11 wnt-11	Danio rerio	7955	4	GTPase activator activity Kupffer's vesicle development camera-type eye development canonical Wnt signaling pathway cell fate commitment cell migration cell migration involved in gastrulation cell-cell adhesion central nervous system development convergent extension convergent extension involved in axis elongation convergent extension involved in gastrulation cytokine activity cytoplasm embryonic eye morphogenesis establishment of mitotic spindle orientation extracellular space eye field cell fate commitment involved in camera-type eye formation frizzled binding gastrulation with mouth forming second heart development heart looping mediolateral intercalation mesodermal cell migration negative regulation of DNA-templated transcription negative regulation of canonical Wnt signaling pathway negative regulation of cell growth negative regulation of cell migration neural plate morphogenesis neuroendocrine cell differentiation neuron differentiation non-canonical Wnt signaling pathway plasma membrane positive regulation of DNA-templated transcription positive regulation of GTPase activity positive regulation of protein kinase C signaling positive regulation of stress fiber assembly protein heterodimerization activity protein kinase activator activity protein localization protein localization to cell surface protein phosphorylation regulation of endocytosis secondary palate development signal transduction	GO:0000132 GO:0001702 GO:0001839 GO:0001947 GO:0005096 GO:0005109 GO:0005125 GO:0005615 GO:0005737 GO:0005886 GO:0006468 GO:0007165 GO:0007417 GO:0007507 GO:0008078 GO:0008104 GO:0016477 GO:0030100 GO:0030182 GO:0030295 GO:0030308 GO:0030336 GO:0034394 GO:0035567 GO:0042074 GO:0043010 GO:0043547 GO:0045165 GO:0045892 GO:0045893 GO:0046982 GO:0048048 GO:0051496 GO:0060026 GO:0060027 GO:0060028 GO:0060031 GO:0060070 GO:0060898 GO:0061101 GO:0062009 GO:0070121 GO:0090037 GO:0090090 GO:0098609
Protein Wnt-11	B2GUT4	wnt11	wnt11r	wnt11 wnt11r	Xenopus tropicalis	8364	4	GTPase activator activity cell migration involved in gastrulation cytoplasm dorsal fin development embryonic viscerocranium morphogenesis extracellular region heart looping heart morphogenesis negative regulation of DNA-templated transcription negative regulation of canonical Wnt signaling pathway negative regulation of cell growth negative regulation of cell migration neural crest cell migration neuroendocrine cell differentiation neuromast development non-canonical Wnt signaling pathway pharyngeal system development positive regulation of DNA-templated transcription positive regulation of GTPase activity positive regulation of JNK cascade positive regulation of protein kinase C signaling positive regulation of stress fiber assembly pronephros development protein kinase activator activity protein localization to cell surface protein phosphorylation regulation of gastrulation secondary palate development signal transduction signaling receptor binding	GO:0001755 GO:0001947 GO:0003007 GO:0005096 GO:0005102 GO:0005576 GO:0005737 GO:0006468 GO:0007165 GO:0010470 GO:0030295 GO:0030308 GO:0030336 GO:0033337 GO:0034394 GO:0035567 GO:0042074 GO:0043547 GO:0045892 GO:0045893 GO:0046330 GO:0048703 GO:0048793 GO:0048884 GO:0051496 GO:0060037 GO:0061101 GO:0062009 GO:0090037 GO:0090090
Protein Wnt-11	Q670P5	wnt11	wnt11r	wnt11 wnt11r	Xenopus laevis	8355	3	dorsal fin development embryonic axis specification extracellular region gastrulation heart morphogenesis negative regulation of canonical Wnt signaling pathway neural crest cell migration non-canonical Wnt signaling pathway positive regulation of JNK cascade pronephros development regulation of gastrulation signaling receptor binding	GO:0000578 GO:0001755 GO:0003007 GO:0005102 GO:0005576 GO:0007369 GO:0010470 GO:0033337 GO:0035567 GO:0046330 GO:0048793 GO:0090090