GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GO Labels	GO IDs
Voltage-dependent L-type calcium channel subunit alpha	A0A2K5SDG9	CACNA1C		CACNA1C	Cebus imitator	2715852	1		T-tubule calmodulin binding dendrite metal ion binding perikaryon postsynaptic density membrane regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005516 GO:0005891 GO:0030315 GO:0030425 GO:0034765 GO:0043204 GO:0046872 GO:0098839
P2X purinoceptor	A0A2U3VLS2	P2RX4		P2RX4	Odobenus rosmarus divergens	9708	1		ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase	A0A8B6EC82	MGAL_10B077013		MGAL_10B077013	Mytilus galloprovincialis	29158	1		extracellular region galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity membrane serine-type endopeptidase inhibitor activity	GO:0004867 GO:0005576 GO:0015018 GO:0016020
Kininogen-1	P01042	KNG1	BDK KNG	KNG1 BDK KNG	Homo sapiens	9606	32	92	blood coagulation blood microparticle collagen-containing extracellular matrix cysteine-type endopeptidase inhibitor activity endoplasmic reticulum lumen extracellular exosome extracellular region extracellular space heparin binding hormone activity inflammatory response negative regulation of blood coagulation negative regulation of cell adhesion negative regulation of proteolysis plasma membrane platelet alpha granule lumen positive regulation of apoptotic process positive regulation of cytosolic calcium ion concentration signaling receptor binding vasodilation zinc ion binding	GO:0004869 GO:0005102 GO:0005179 GO:0005576 GO:0005615 GO:0005788 GO:0005886 GO:0006954 GO:0007162 GO:0007204 GO:0007596 GO:0008201 GO:0008270 GO:0030195 GO:0031093 GO:0042311 GO:0043065 GO:0045861 GO:0062023 GO:0070062 GO:0072562
Voltage-dependent L-type calcium channel subunit alpha (Fragment)	A0A091H825	N303_08695		N303_08695	Cuculus canorus	55661	1		metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
ABC multidrug transporter MDR1	F2SHL1	MDR1	pdr1	MDR1 pdr1	Trichophyton rubrum CBS 118892	559305	7		ABC-type transporter activity ATP binding ATP hydrolysis activity plasma membrane	GO:0005524 GO:0005886 GO:0016887 GO:0140359
Matrix protein 2	A0A1Q0GUM5	M2	M	M2 M	Influenza A virus (A/Rhode Island/31/2016(H3N2))	1948988	1		host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Xyloglucan endotransglucosylase/hydrolase	C0IRH9	DVH24_027842		DVH24_027842	Malus domestica	3750	1		apoplast cell wall biogenesis cell wall organization hydrolase activity, hydrolyzing O-glycosyl compounds xyloglucan metabolic process xyloglucan:xyloglucosyl transferase activity	GO:0004553 GO:0010411 GO:0016762 GO:0042546 GO:0048046 GO:0071555
Myocardin-related transcription factor A	Q8K4J6	Mrtfa	Bsac Mal Mkl1	Mrtfa Bsac Mal Mkl1	Mus musculus	10090	3	1	DNA-binding transcription factor activity actin binding actin cytoskeleton organization actin monomer binding cytoplasm cytosol forebrain development leucine zipper domain binding molecular adaptor activity negative regulation of apoptotic signaling pathway neuron migration neuron projection development nucleoplasm nucleus positive regulation of DNA-templated transcription positive regulation of miRNA transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II smooth muscle cell differentiation transcription cis-regulatory region binding transcription coactivator activity wound healing, spreading of cells	GO:0000976 GO:0001764 GO:0003700 GO:0003713 GO:0003779 GO:0003785 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006357 GO:0030036 GO:0030900 GO:0031175 GO:0043522 GO:0044319 GO:0045893 GO:0045944 GO:0051145 GO:0060090 GO:1902895 GO:2001234
Paraoxonase	A0A096MTS0	PON1		PON1	Papio anubis	9555	3		acyl-L-homoserine-lactone lactonohydrolase activity aromatic compound catabolic process aryldialkylphosphatase activity arylesterase activity calcium ion binding carboxylic acid catabolic process cholesterol metabolic process organophosphate catabolic process phosphatidylcholine metabolic process phospholipid binding positive regulation of cholesterol efflux protein homodimerization activity response to toxic substance spherical high-density lipoprotein particle	GO:0004063 GO:0004064 GO:0005509 GO:0005543 GO:0008203 GO:0009636 GO:0010875 GO:0019439 GO:0034366 GO:0042803 GO:0046395 GO:0046434 GO:0046470 GO:0102007