GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GO Labels	GO IDs
MHC class I antigen (Fragment)	D5G241	HLA-C	HLA-C	Homo sapiens	9606	1
Potassium channel subfamily K member	A0A452FAZ2	KCNK7	KCNK7	Capra hircus	9925	1		membrane potassium channel activity	GO:0005267 GO:0016020
Lanosterol synthase	Q8BLN5	Lss	Lss	Mus musculus	10090		1	cholesterol biosynthetic process endoplasmic reticulum membrane lanosterol synthase activity lipid droplet regulation of protein stability steroid biosynthetic process sterol metabolic process triterpenoid biosynthetic process	GO:0000250 GO:0005789 GO:0005811 GO:0006694 GO:0006695 GO:0016104 GO:0016125 GO:0031647
Non-structural glycoprotein 4	X2FP65	NSP4	NSP4	Rotavirus A	28875	2		extracellular region host caveola host cell rough endoplasmic reticulum membrane induction by virus of host autophagy membrane metal ion binding monoatomic ion channel activity protein complex oligomerization toxin activity virus-mediated pore formation in host cell membrane	GO:0005216 GO:0005576 GO:0016020 GO:0039520 GO:0039707 GO:0044155 GO:0044169 GO:0046872 GO:0051259 GO:0090729
FIC domain-containing protein (Fragment)	A0A4Y5U4R8	FICD	FICD	Hyperolius ademetzi	2517384	1		ATP binding	GO:0005524
GAF domain-containing protein	Q4DTJ6	Tc00.1047053507053.90	Tc00.1047053507053.90	Trypanosoma cruzi strain CL Brener	353153		1
Rhodopsin	A0A9B0TR11	RHO	RHO	Chrysochloris asiatica	185453	2		G protein-coupled receptor activity membrane metal ion binding photoreceptor activity phototransduction visual perception	GO:0004930 GO:0007601 GO:0007602 GO:0009881 GO:0016020 GO:0046872
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	O15294	OGT	OGT	Homo sapiens	9606	8	1	NSL complex acetylglucosaminyltransferase activity apoptotic process cell projection chromatin DNA binding chromatin organization circadian regulation of gene expression cytosol glutamatergic synapse hemopoiesis histone acetyltransferase complex mitochondrial membrane mitophagy negative regulation of cell migration negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of protein ubiquitination negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II negative regulation of transforming growth factor beta receptor signaling pathway nucleoplasm nucleus obsolete Sin3 complex obsolete regulation of dosage compensation by inactivation of X chromosome phosphatidylinositol-3,4,5-trisphosphate binding plasma membrane positive regulation of DNA-templated transcription positive regulation of cold-induced thermogenesis positive regulation of histone H3-K4 methylation positive regulation of lipid biosynthetic process positive regulation of proteolysis positive regulation of stem cell population maintenance positive regulation of transcription by RNA polymerase II positive regulation of transcription from RNA polymerase II promoter by glucose positive regulation of translation protein N-acetylglucosaminyltransferase complex protein O-acetylglucosaminyltransferase activity protein O-linked glycosylation protein processing protein-containing complex regulation of Rac protein signal transduction regulation of gluconeogenesis regulation of glycolytic process regulation of insulin receptor signaling pathway regulation of necroptotic process regulation of neurotransmitter receptor localization to postsynaptic specialization membrane regulation of synapse assembly regulation of transcription by RNA polymerase II response to insulin response to nutrient signal transduction	GO:0000122 GO:0000123 GO:0000423 GO:0000432 GO:0005547 GO:0005634 GO:0005654 GO:0005829 GO:0005886 GO:0006110 GO:0006111 GO:0006325 GO:0006357 GO:0006493 GO:0006915 GO:0007165 GO:0007584 GO:0008375 GO:0016485 GO:0016580 GO:0017122 GO:0030097 GO:0030336 GO:0030512 GO:0031397 GO:0031490 GO:0031966 GO:0032435 GO:0032868 GO:0032922 GO:0032991 GO:0035020 GO:0042995 GO:0044545 GO:0045727 GO:0045862 GO:0045893 GO:0045944 GO:0046626 GO:0046889 GO:0051571 GO:0051963 GO:0060544 GO:0097363 GO:0098696 GO:0098978 GO:0120162 GO:1900095 GO:1902455 GO:1902459
Prothrombin	A0A6J3IBC6	F2	F2	Sapajus apella	9515	3		acute-phase response blood coagulation calcium ion binding endoplasmic reticulum lumen extracellular region proteolysis serine-type endopeptidase activity	GO:0004252 GO:0005509 GO:0005576 GO:0005788 GO:0006508 GO:0006953 GO:0007596
Peptidylglycine alpha-amidating monooxygenase	F1MZB4	PAM	PAM	Bos taurus	9913	1		L-ascorbic acid binding copper ion binding extracellular region peptide amidation peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity response to zinc ion transport vesicle membrane zinc ion binding	GO:0001519 GO:0004504 GO:0004598 GO:0005507 GO:0005576 GO:0008270 GO:0010043 GO:0030658 GO:0031418