GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GO Labels	GO IDs
Class V chitinase CHIT5	A0A1B1J8Z2	CHIT5		CHIT5	Lotus japonicus	34305	6		chitin binding chitin catabolic process chitinase activity defense response to fungus nodulation polysaccharide catabolic process	GO:0000272 GO:0004568 GO:0006032 GO:0008061 GO:0009877 GO:0050832
Xyloglucan endotransglucosylase/hydrolase	A0A835E3N4	HU200_059348		HU200_059348	Digitaria exilis	1010633	1		apoplast cell wall biogenesis cell wall organization hydrolase activity, hydrolyzing O-glycosyl compounds xyloglucan metabolic process xyloglucan:xyloglucosyl transferase activity	GO:0004553 GO:0010411 GO:0016762 GO:0042546 GO:0048046 GO:0071555
Interleukin-2	O77620	IL2		IL2	Oryctolagus cuniculus	9986	2		activated T cell proliferation adaptive immune response cytokine activity extracellular space extrinsic apoptotic signaling pathway in absence of ligand growth factor activity interleukin-2 receptor binding interleukin-2-mediated signaling pathway leukocyte activation involved in immune response negative regulation of B cell apoptotic process negative regulation of T-helper 17 cell differentiation negative regulation of inflammatory response negative regulation of lymphocyte proliferation positive regulation of B cell proliferation positive regulation of activated T cell proliferation positive regulation of interleukin-17 production positive regulation of isotype switching to IgG isotypes positive regulation of plasma cell differentiation positive regulation of transcription by RNA polymerase II positive regulation of type II interferon production positive regulation of tyrosine phosphorylation of STAT protein regulation of CD4-positive, alpha-beta T cell proliferation regulation of T cell homeostatic proliferation transcription by RNA polymerase II	GO:0002250 GO:0002366 GO:0002903 GO:0005125 GO:0005134 GO:0005615 GO:0006366 GO:0008083 GO:0030890 GO:0032729 GO:0032740 GO:0038110 GO:0042104 GO:0042531 GO:0045944 GO:0046013 GO:0048304 GO:0050672 GO:0050728 GO:0050798 GO:0097192 GO:1900100 GO:2000320 GO:2000561
Vacuolar protein sorting/targeting protein 10	C1GTA5	VPS10		VPS10	Paracoccidioides lutzii Pb01	502779	4		Golgi apparatus intracellular transport membrane protein transport	GO:0005794 GO:0015031 GO:0016020 GO:0046907
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase	A0A2U3XDM0	B3GAT2		B3GAT2	Leptonychotes weddellii	9713	1		Golgi membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity metal ion binding	GO:0000139 GO:0015018 GO:0046872
Potassium channel domain-containing protein	A0A5N3WSE0	FD754_008896		FD754_008896	Muntiacus muntjak	9888	1		membrane potassium channel activity	GO:0005267 GO:0016020
G10 protein	V5AWF3	TCDM_06572		TCDM_06572	Trypanosoma cruzi Dm28c	1416333		1	nucleus	GO:0005634
Taste receptor type 1 member 1	Q99PG6	Tas1r1	Gpr70 T1r1 Tr1	Tas1r1 Gpr70 T1r1 Tr1	Mus musculus	10090	7		G protein-coupled receptor activity plasma membrane sensory perception of umami taste taste receptor activity	GO:0004930 GO:0005886 GO:0008527 GO:0050917
receptor protein-tyrosine kinase (Fragment)	A0A7K4Q5D6	Fgfr2		Fgfr2	Melospiza melodia	44397	8		ATP binding fibroblast growth factor receptor activity plasma membrane positive regulation of cell population proliferation	GO:0005007 GO:0005524 GO:0005886 GO:0008284
Protein wntless	B4LC58	wls		wls	Drosophila virilis	7244	2		Golgi membrane Golgi to plasma membrane protein transport Wnt protein secretion Wnt signaling pathway Wnt-protein binding cell projection compound eye morphogenesis cuticle pattern formation early endosome endoplasmic reticulum membrane endosome membrane extracellular exosome imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis multivesicular body neuromuscular junction plasma membrane positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway positive regulation of protein secretion postsynaptic membrane presynaptic membrane regulation of intracellular protein transport segment polarity determination synaptic vesicle membrane trans-synaptic signaling via exosome	GO:0000139 GO:0001745 GO:0005769 GO:0005771 GO:0005789 GO:0005886 GO:0007367 GO:0007480 GO:0008587 GO:0010008 GO:0016055 GO:0017147 GO:0030177 GO:0030672 GO:0031594 GO:0033157 GO:0035017 GO:0042734 GO:0042995 GO:0043001 GO:0045211 GO:0050714 GO:0061355 GO:0061357 GO:0070062 GO:0099157