GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GO Labels	GO IDs
Voltage-dependent L-type calcium channel subunit alpha-1D-like protein	A0A498M7D9	ROHU_037211		ROHU_037211	Labeo rohita	84645	1		metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Matrix protein 2	V9SRV6	M2	M	M2 M	Influenza A virus (A/Peru/PER209/2012(H3N2))	1427922	1		host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Matrix protein 2	Q00PY2	M2	M	M2 M	Influenza A virus (A/Western Australia/72/2005(H3N2))	390226	1		host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Matrix protein 2	A0A0N9R029	M2	M	M2 M	Influenza A virus (A/District Of Columbia/03/2014(H3N2))	1731090	1		host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Voltage-dependent L-type calcium channel subunit alpha	A0A8B9YPS7	CACNA1F		CACNA1F	Bos grunniens	30521	1		metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
STE20-related kinase adapter protein alpha	Q7RTN6	STRADA	LYK5 STRAD	STRADA LYK5 STRAD	Homo sapiens	9606		1	ATP binding G1 to G0 transition activation of protein kinase activity cytoplasm cytosol intracellular protein-containing complex kinase binding nucleoplasm nucleus protein export from nucleus protein kinase activator activity protein serine/threonine kinase activator activity serine/threonine protein kinase complex	GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006611 GO:0019900 GO:0030295 GO:0032147 GO:0043539 GO:0070314 GO:0140535 GO:1902554
Papilin	O95428	PAPLN		PAPLN	Homo sapiens	9606	22	4	extracellular matrix organization extracellular region serine-type endopeptidase inhibitor activity	GO:0004867 GO:0005576 GO:0030198
ubiquitinyl hydrolase 1	A0A8I6AL23	Tnfaip3		Tnfaip3	Rattus norvegicus	10116		1	B-1 B cell homeostasis DNA binding K63-linked deubiquitinase activity K63-linked polyubiquitin modification-dependent protein binding cell migration cellular response to hydrogen peroxide cellular response to lipopolysaccharide cysteine-type deubiquitinase activity cytoplasm cytoskeleton organization establishment of protein localization to vacuole identical protein binding kinase binding negative regulation of B cell activation negative regulation of CD40 signaling pathway negative regulation of canonical NF-kappaB signal transduction negative regulation of chronic inflammatory response negative regulation of endothelial cell apoptotic process negative regulation of extrinsic apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of inflammatory response negative regulation of innate immune response negative regulation of interleukin-1 beta production negative regulation of interleukin-2 production negative regulation of interleukin-6 production negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway negative regulation of protein ubiquitination negative regulation of smooth muscle cell proliferation negative regulation of toll-like receptor 3 signaling pathway negative regulation of toll-like receptor 5 signaling pathway negative regulation of tumor necrosis factor production nucleus positive regulation of Wnt signaling pathway positive regulation of hepatocyte proliferation positive regulation of protein catabolic process protease binding protein self-association proteolysis regulation of germinal center formation response to molecule of bacterial origin response to muramyl dipeptide tolerance induction to lipopolysaccharide ubiquitin binding ubiquitin-protein transferase activity zinc ion binding	GO:0001922 GO:0002020 GO:0002237 GO:0002634 GO:0002677 GO:0003677 GO:0004842 GO:0004843 GO:0005634 GO:0005737 GO:0006508 GO:0007010 GO:0008270 GO:0016477 GO:0019900 GO:0030177 GO:0031397 GO:0032495 GO:0032691 GO:0032703 GO:0032715 GO:0032720 GO:0034140 GO:0034148 GO:0042802 GO:0043124 GO:0043130 GO:0043621 GO:0045732 GO:0045824 GO:0048662 GO:0050728 GO:0050869 GO:0061578 GO:0070301 GO:0070429 GO:0070433 GO:0070530 GO:0071222 GO:0072573 GO:0072666 GO:1902042 GO:2000347 GO:2000349 GO:2000352 GO:2001237
Xyloglucan endotransglucosylase/hydrolase	A0A068TQI9	GSCOC_T00022745001		GSCOC_T00022745001	Coffea canephora	49390	1		apoplast cell wall biogenesis cell wall organization hydrolase activity, hydrolyzing O-glycosyl compounds xyloglucan metabolic process xyloglucan:xyloglucosyl transferase activity	GO:0004553 GO:0010411 GO:0016762 GO:0042546 GO:0048046 GO:0071555
Rhodopsin	A0A2R3ZCJ0	rho		rho	Limanda limanda	27771	2		G protein-coupled receptor activity membrane metal ion binding photoreceptor activity phototransduction visual perception	GO:0004930 GO:0007601 GO:0007602 GO:0009881 GO:0016020 GO:0046872