GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of GlyTouCan IDs	GO Labels	GO IDs
Protein SPT2 homolog	Q68D10	SPTY2D1		SPTY2D1	Homo sapiens	9606	1	DNA binding RNA polymerase I core binding heterochromatin formation histone binding histone chaperone activity nucleolus nucleoplasm nucleosome assembly regulation of DNA-templated transcription transcription by RNA polymerase I	GO:0001042 GO:0003677 GO:0005654 GO:0005730 GO:0006334 GO:0006355 GO:0006360 GO:0031507 GO:0042393 GO:0140713
5'-AMP-activated protein kinase catalytic subunit alpha-1	Q13131	PRKAA1	AMPK1	PRKAA1 AMPK1	Homo sapiens	9606	1	AMP-activated protein kinase activity ATP binding CAMKK-AMPK signaling cascade Wnt signaling pathway [acetyl-CoA carboxylase] kinase activity [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity apical plasma membrane autophagy axon bile acid and bile salt transport bile acid signaling pathway cAMP-dependent protein kinase activity cellular response to calcium ion cellular response to ethanol cellular response to glucose starvation cellular response to glucose stimulus cellular response to hydrogen peroxide cellular response to hypoxia cellular response to nutrient levels cellular response to organonitrogen compound cellular response to oxidative stress cellular response to prostaglandin E stimulus cellular response to xenobiotic stimulus cholesterol biosynthetic process chromatin chromatin binding cold acclimation cytoplasm cytosol dendrite energy homeostasis fatty acid biosynthetic process fatty acid homeostasis fatty acid oxidation glucose homeostasis glucose metabolic process histone H2BS36 kinase activity intracellular signal transduction lipid biosynthetic process lipid droplet disassembly metal ion binding motor behavior negative regulation of TOR signaling negative regulation of TORC1 signaling negative regulation of apoptotic process negative regulation of gene expression negative regulation of glucosylceramide biosynthetic process negative regulation of hepatocyte apoptotic process negative regulation of insulin receptor signaling pathway negative regulation of lipid catabolic process negative regulation of tubulin deacetylation neuron cellular homeostasis neuronal cell body nuclear speck nucleoplasm nucleotide-activated protein kinase complex nucleus positive regulation of DNA-templated transcription positive regulation of adipose tissue development positive regulation of autophagy positive regulation of cell population proliferation positive regulation of cholesterol biosynthetic process positive regulation of gene expression positive regulation of glycolytic process positive regulation of mitochondrial transcription positive regulation of peptidyl-lysine acetylation positive regulation of protein localization positive regulation of protein targeting to mitochondrion positive regulation of skeletal muscle tissue development protein kinase activity protein localization to lipid droplet protein phosphorylation protein serine kinase activity protein serine/threonine kinase activity regulation of bile acid secretion regulation of circadian rhythm regulation of microtubule cytoskeleton organization regulation of peptidyl-serine phosphorylation regulation of stress granule assembly regulation of vesicle-mediated transport response to UV response to activity response to caffeine response to estrogen response to gamma radiation response to hypoxia rhythmic process signal transduction tau protein binding tau-protein kinase activity	GO:0000785 GO:0001666 GO:0003682 GO:0004672 GO:0004674 GO:0004679 GO:0004691 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006006 GO:0006468 GO:0006633 GO:0006695 GO:0006914 GO:0007165 GO:0008284 GO:0008610 GO:0009411 GO:0009631 GO:0010332 GO:0010508 GO:0010628 GO:0010629 GO:0014823 GO:0015721 GO:0016055 GO:0016324 GO:0016607 GO:0019395 GO:0030424 GO:0030425 GO:0031000 GO:0031588 GO:0031669 GO:0032007 GO:0033135 GO:0034599 GO:0035556 GO:0038183 GO:0042149 GO:0042593 GO:0042752 GO:0043025 GO:0043066 GO:0043627 GO:0045542 GO:0045821 GO:0045893 GO:0046318 GO:0046627 GO:0046872 GO:0047322 GO:0048156 GO:0048511 GO:0048643 GO:0050321 GO:0050405 GO:0050995 GO:0055089 GO:0060627 GO:0061744 GO:0061762 GO:0062028 GO:0070050 GO:0070301 GO:0070507 GO:0071277 GO:0071333 GO:0071361 GO:0071380 GO:0071417 GO:0071456 GO:0071466 GO:0097009 GO:0106310 GO:0120188 GO:0140823 GO:1903109 GO:1903829 GO:1903944 GO:1903955 GO:1904179 GO:1904262 GO:1904428 GO:1905691 GO:1990044 GO:2000758
Presequence protease, mitochondrial	Q8K411	Pitrm1	Kiaa1104 Ntup1	Pitrm1 Kiaa1104 Ntup1	Mus musculus	10090	1	metalloendopeptidase activity metallopeptidase activity mitochondrial matrix mitochondrion protein processing proteolysis zinc ion binding	GO:0004222 GO:0005739 GO:0005759 GO:0006508 GO:0008237 GO:0008270 GO:0016485
Ubiquitin-conjugating enzyme E2 variant 2	A6X925	Ube2v2		Ube2v2	Mus musculus	10090	1
Dihydrolipoamide acetyltransferase	V5B0M9	TCDM_04684		TCDM_04684	Trypanosoma cruzi Dm28c	1416333	1	acetyl-CoA biosynthetic process from pyruvate pyruvate dehydrogenase complex transferase activity	GO:0006086 GO:0016740 GO:0045254
Zinc finger protein 37	P17141	Zfp37	Zfp-37	Zfp37 Zfp-37	Mus musculus	10090	1	DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding germ cell development negative regulation of transcription by RNA polymerase II nucleus spermatogenesis zinc ion binding	GO:0000122 GO:0000977 GO:0001227 GO:0005634 GO:0007281 GO:0007283 GO:0008270
UDP-GlcNAc:polypeptide N-acetylglucosaminyltransferase	V5AZB4	TCDM_05104		TCDM_05104	Trypanosoma cruzi Dm28c	1416333	1	membrane	GO:0016020
BRO1 domain-containing protein	V5BQH3	TCDM_04487		TCDM_04487	Trypanosoma cruzi Dm28c	1416333	1
ADP-ribosylation factor-like protein, putative	Q4DZM9	Tc00.1047053504147.160		Tc00.1047053504147.160	Trypanosoma cruzi strain CL Brener	353153	1	GTP binding GTPase activity protein transport	GO:0003924 GO:0005525 GO:0015031
Ras-related protein Rab-8A	P55258	Rab8a	Mel Rab8	Rab8a Mel Rab8	Mus musculus	10090	1	GDP binding GTP binding GTPase activity Golgi apparatus Golgi organization Golgi vesicle fusion to target membrane autophagy axonogenesis cellular response to insulin stimulus centriole centrosome ciliary basal body ciliary base ciliary membrane cilium cilium assembly cytoplasmic vesicle cytoplasmic vesicle membrane dendrite dendritic spine endocytic recycling endosome glutamatergic synapse midbody myosin V binding neuron projection neuronal cell body neurotransmitter receptor transport to postsynaptic membrane neurotransmitter receptor transport, endosome to postsynaptic membrane non-motile cilium phagocytic vesicle phagocytic vesicle membrane plasma membrane postsynaptic density protein kinase binding protein localization to cilium protein localization to plasma membrane protein secretion protein tyrosine kinase binding recycling endosome recycling endosome membrane regulation of autophagy regulation of exocytosis regulation of long-term neuronal synaptic plasticity regulation of protein localization regulation of protein transport small GTPase binding synapse synaptic vesicle trans-Golgi network transport vesicle vesicle docking involved in exocytosis vesicle-mediated transport in synapse	GO:0003924 GO:0005525 GO:0005768 GO:0005794 GO:0005813 GO:0005814 GO:0005886 GO:0005929 GO:0006904 GO:0006914 GO:0007030 GO:0007409 GO:0008021 GO:0009306 GO:0010506 GO:0014069 GO:0017157 GO:0019003 GO:0019901 GO:0030140 GO:0030425 GO:0030496 GO:0030659 GO:0030670 GO:0031267 GO:0031410 GO:0031489 GO:0032456 GO:0032869 GO:0032880 GO:0036064 GO:0043005 GO:0043025 GO:0043197 GO:0045202 GO:0045335 GO:0048169 GO:0048210 GO:0051223 GO:0055037 GO:0055038 GO:0060170 GO:0060271 GO:0061512 GO:0072659 GO:0097546 GO:0097730 GO:0098887 GO:0098969 GO:0098978 GO:0099003 GO:1990782