GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GO Labels	GO IDs
Protein O-mannosyl-transferase 1	Q99PR0	Pomt1	Pomt1	Rattus norvegicus	10116	3	2	acrosomal vesicle dolichyl-phosphate-mannose-protein mannosyltransferase activity endoplasmic reticulum membrane extracellular matrix organization mannosyltransferase activity positive regulation of protein O-linked glycosylation protein O-linked mannosylation sarcoplasmic reticulum	GO:0000030 GO:0001669 GO:0004169 GO:0005789 GO:0016529 GO:0030198 GO:0035269 GO:1904100
Nuclear receptor coactivator	D4A3Q3	Ncoa1	Ncoa1	Rattus norvegicus	10116		1	DNA binding RNA polymerase II transcription regulator complex RNA polymerase II transcription regulatory region sequence-specific DNA binding cellular response to Thyroglobulin triiodothyronine cellular response to hormone stimulus cerebellum development cerebral cortex development chromatin chromatin binding estrous cycle hippocampus development hypothalamus development labyrinthine layer morphogenesis lactation mRNA transcription by RNA polymerase II male gonad development male mating behavior nuclear estrogen receptor binding nuclear receptor binding nuclear receptor coactivator activity nuclear retinoic acid receptor binding nuclear retinoid X receptor binding nucleus positive regulation of DNA-templated transcription positive regulation of apoptotic process positive regulation of female receptivity positive regulation of neuron differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription from RNA polymerase II promoter by galactose protein dimerization activity protein-containing complex protein-containing complex binding regulation of thyroid hormone mediated signaling pathway response to estradiol response to hormone response to progesterone response to retinoic acid transcription coactivator activity transcription regulator complex	GO:0000435 GO:0000785 GO:0000977 GO:0002155 GO:0003677 GO:0003682 GO:0003713 GO:0005634 GO:0005667 GO:0007595 GO:0008584 GO:0009725 GO:0016922 GO:0021549 GO:0021766 GO:0021854 GO:0021987 GO:0030331 GO:0030374 GO:0032355 GO:0032526 GO:0032570 GO:0032870 GO:0032991 GO:0042789 GO:0042974 GO:0043065 GO:0044849 GO:0044877 GO:0045666 GO:0045893 GO:0045925 GO:0045944 GO:0046965 GO:0046983 GO:0060179 GO:0060713 GO:0090575 GO:1904017
ER degradation-enhancing alpha-mannosidase-like protein 2	Q8BJT9	Edem2	Edem2	Mus musculus	10090	4		calcium ion binding carbohydrate metabolic process endoplasmic reticulum endoplasmic reticulum lumen mannosyl-oligosaccharide 1,2-alpha-mannosidase activity membrane positive regulation of retrograde protein transport, ER to cytosol response to unfolded protein ubiquitin-dependent glycoprotein ERAD pathway	GO:0004571 GO:0005509 GO:0005783 GO:0005788 GO:0005975 GO:0006986 GO:0016020 GO:0097466 GO:1904154
Basement membrane proteoglycan	H9G349	unc-52	unc-52	Caenorhabditis elegans	6239	1		basement membrane cell migration embryo development ending in birth or egg hatching fibroblast growth factor receptor signaling pathway hemidesmosome assembly locomotion muscle organ development muscle organ morphogenesis positive regulation of locomotion structural molecule activity	GO:0005198 GO:0005604 GO:0007517 GO:0008543 GO:0009792 GO:0016477 GO:0031581 GO:0040011 GO:0040017 GO:0048644
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase	A0A3P8UKM0	B3GAT1	B3GAT1	Cynoglossus semilaevis	244447	1		Golgi membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity metal ion binding	GO:0000139 GO:0015018 GO:0046872
Rhodopsin (Fragment)	A0A8F0FS79	Rhod	Rhod	Quasipaa exilispinosa	342815	1		G protein-coupled receptor activity membrane metal ion binding photoreceptor outer segment phototransduction visual perception	GO:0001750 GO:0004930 GO:0007601 GO:0007602 GO:0016020 GO:0046872
Voltage-dependent L-type calcium channel subunit alpha	A0A6J3FWF7	CACNA1C	CACNA1C	Sapajus apella	9515	1		T-tubule calmodulin binding dendrite metal ion binding perikaryon postsynaptic density membrane regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005516 GO:0005891 GO:0030315 GO:0030425 GO:0034765 GO:0043204 GO:0046872 GO:0098839
Hyaluronidase	A0A452TH52	SPAM1	SPAM1	Ursus maritimus	29073	1		carbohydrate metabolic process fusion of sperm to egg plasma membrane involved in single fertilization hyalurononglucosaminidase activity plasma membrane	GO:0004415 GO:0005886 GO:0005975 GO:0007342
CASP-like protein 1E1	B9RT04	RCOM_0680180	RCOM_0680180	Ricinus communis	3988	1		plasma membrane	GO:0005886
Carbohydrate sulfotransferase 10	Q6AXM1	chst10	chst10	Danio rerio	7955	3		Golgi membrane carbohydrate biosynthetic process proteoglycan biosynthetic process sulfotransferase activity	GO:0000139 GO:0008146 GO:0016051 GO:0030166