GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GO Labels	GO IDs
Salivary protein 15 Iper-3	C8BKF3	salp15		salp15	Ixodes persulcatus	34615	5		extracellular region	GO:0005576
Hyaluronidase-3	F7HA14	HYAL3		HYAL3	Macaca mulatta	9544	1		acrosomal membrane acrosomal vesicle carbohydrate metabolic process cartilage development cellular response to UV-B cellular response to interleukin-1 cellular response to tumor necrosis factor early endosome endoplasmic reticulum hyaluronan catabolic process hyaluronoglucuronidase activity hyalurononglucosaminidase activity inflammatory response lysosome negative regulation of ovarian follicle development ovarian follicle atresia penetration of zona pellucida plasma membrane positive regulation of acrosomal vesicle exocytosis response to antibiotic response to virus sperm midpiece	GO:0001552 GO:0001669 GO:0002080 GO:0004415 GO:0005764 GO:0005769 GO:0005783 GO:0005886 GO:0005975 GO:0006954 GO:0007341 GO:0009615 GO:0030214 GO:0033906 GO:0046677 GO:0051216 GO:0071347 GO:0071356 GO:0071493 GO:0097225 GO:2000355 GO:2000368
Carcinoembryonic antigen-related cell adhesion molecule 18	A8MTB9	CEACAM18		CEACAM18	Homo sapiens	9606	5	1
Matrix protein 2	A0A2D3R6E2	M2	M	M2 M	Influenza A virus (A/South Australia/90/2016(H3N2))	2043952	1		host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Pre-glycoprotein polyprotein GP complex	A0A3S7SZ47	GPC		GPC	Mammarenavirus lassaense	3052310	11		fusion of virus membrane with host endosome membrane host cell Golgi membrane host cell endoplasmic reticulum membrane host cell plasma membrane membrane metal ion binding receptor-mediated endocytosis of virus by host cell viral envelope virion attachment to host cell virion membrane	GO:0016020 GO:0019031 GO:0019062 GO:0019065 GO:0020002 GO:0039654 GO:0044167 GO:0044178 GO:0046872 GO:0055036
Voltage-dependent L-type calcium channel subunit alpha	A0A674E704	CACNA1D		CACNA1D	Salmo trutta	8032	1		metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Hyaluronidase (Fragment)	A0A7K6DWY0	Hyal		Hyal	Grantiella picta	266360	1		carbohydrate metabolic process hyalurononglucosaminidase activity	GO:0004415 GO:0005975
Matrix protein 2	A9C9B2	M2	M	M2 M	Influenza A virus (A/Colorado/UR06-0024/2007(H3N2))	480705	1		host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Plastin-2	P13796	LCP1	PLS2	LCP1 PLS2	Homo sapiens	9606	8	1	GTPase binding T cell activation involved in immune response actin binding actin crosslink formation actin cytoskeleton actin filament actin filament binding actin filament bundle actin filament bundle assembly actin filament network formation animal organ regeneration calcium ion binding cell junction cell migration cortical actin cytoskeleton organization cytoplasm cytosol extracellular exosome extracellular matrix disassembly extracellular space filopodium focal adhesion glial cell projection integrin binding perinuclear region of cytoplasm phagocytic cup plasma membrane podosome positive regulation of podosome assembly protein kinase A signaling regulation of intracellular protein transport ruffle ruffle membrane	GO:0001726 GO:0001891 GO:0002102 GO:0002286 GO:0003779 GO:0005178 GO:0005509 GO:0005615 GO:0005737 GO:0005829 GO:0005884 GO:0005886 GO:0005925 GO:0010737 GO:0015629 GO:0016477 GO:0022617 GO:0030054 GO:0030175 GO:0030866 GO:0031100 GO:0032432 GO:0032587 GO:0033157 GO:0048471 GO:0051015 GO:0051017 GO:0051020 GO:0051639 GO:0051764 GO:0070062 GO:0071803 GO:0097386
Mediator of RNA polymerase II transcription subunit 12-like protein	Q86YW9	MED12L	KIAA1635 TNRC11L TRALP TRALPUSH	MED12L KIAA1635 TNRC11L TRALP TRALPUSH	Homo sapiens	9606		1	beta-catenin binding mediator complex positive regulation of transcription by RNA polymerase II transcription coactivator activity	GO:0003713 GO:0008013 GO:0016592 GO:0045944