GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GO Labels	GO IDs
Plastin-2	P13796	LCP1	PLS2	LCP1 PLS2	Homo sapiens	9606	8	1	GTPase binding T cell activation involved in immune response actin binding actin crosslink formation actin cytoskeleton actin filament actin filament binding actin filament bundle actin filament bundle assembly actin filament network formation animal organ regeneration calcium ion binding cell junction cell migration cortical actin cytoskeleton organization cytoplasm cytosol extracellular exosome extracellular matrix disassembly extracellular space filopodium focal adhesion glial cell projection integrin binding perinuclear region of cytoplasm phagocytic cup plasma membrane podosome positive regulation of podosome assembly protein kinase A signaling regulation of intracellular protein transport ruffle ruffle membrane	GO:0001726 GO:0001891 GO:0002102 GO:0002286 GO:0003779 GO:0005178 GO:0005509 GO:0005615 GO:0005737 GO:0005829 GO:0005884 GO:0005886 GO:0005925 GO:0010737 GO:0015629 GO:0016477 GO:0022617 GO:0030054 GO:0030175 GO:0030866 GO:0031100 GO:0032432 GO:0032587 GO:0033157 GO:0048471 GO:0051015 GO:0051017 GO:0051020 GO:0051639 GO:0051764 GO:0070062 GO:0071803 GO:0097386
Mediator of RNA polymerase II transcription subunit 12-like protein	Q86YW9	MED12L	KIAA1635 TNRC11L TRALP TRALPUSH	MED12L KIAA1635 TNRC11L TRALP TRALPUSH	Homo sapiens	9606		1	beta-catenin binding mediator complex positive regulation of transcription by RNA polymerase II transcription coactivator activity	GO:0003713 GO:0008013 GO:0016592 GO:0045944
Voltage-dependent P/Q-type calcium channel subunit alpha-1A-like	A0A674C2R6	LOC115170706		LOC115170706	Salmo trutta	8032	1		metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Endothelin-converting enzyme-like 1	Q9JMI0	Ecel1	Dine Xce	Ecel1 Dine Xce	Mus musculus	10090	3		intracellular signal transduction metal ion binding metalloendopeptidase activity neuropeptide signaling pathway plasma membrane protein processing respiratory system process	GO:0003016 GO:0004222 GO:0005886 GO:0007218 GO:0016485 GO:0035556 GO:0046872
Voltage-dependent L-type calcium channel subunit alpha	A0A341BT92	CACNA1S		CACNA1S	Neophocaena asiaeorientalis asiaeorientalis	1706337	1		metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Matrix protein 2	X2DPN5	M2	M	M2 M	Influenza A virus (A/Tennessee/F2018A/2011(H3N2))	1452614	1		host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Fibroblast growth factor receptor	A0A674PB29	fgfr2		fgfr2	Takifugu rubripes	31033	8		ATP binding fibroblast growth factor receptor activity phosphorylation plasma membrane positive regulation of cell population proliferation	GO:0005007 GO:0005524 GO:0005886 GO:0008284 GO:0016310
Proto-oncogene tyrosine-protein kinase receptor Ret	A0A6B0RFM7	E5288_WYG019359		E5288_WYG019359	Bos mutus	72004	1		ATP binding calcium ion binding homophilic cell adhesion via plasma membrane adhesion molecules membrane raft phosphorylation plasma membrane transmembrane receptor protein tyrosine kinase activity	GO:0004714 GO:0005509 GO:0005524 GO:0005886 GO:0007156 GO:0016310 GO:0045121
P2X purinoceptor	A0A7J7UGP6	mPipKuh1_013018		mPipKuh1_013018	Pipistrellus kuhlii	59472	1		ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
Transmembrane protein 182	B2RVY9	Tmem182		Tmem182	Mus musculus	10090	4		muscle organ development myotube cell development involved in skeletal muscle regeneration myotube differentiation involved in skeletal muscle regeneration negative regulation of myoblast differentiation negative regulation of myoblast fusion plasma membrane	GO:0005886 GO:0007517 GO:0014906 GO:0014908 GO:0045662 GO:1901740