GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name ▼ UniProt ID Gene Symbol Gene Symbol Aliases Gene Symbol All Species Taxonomy ID No. of Glycosylation Sites No. of GlyTouCan IDs MCAW IDs Disease Name Aliases Disease Name GO Labels GO IDs
  • Plcd1
  • Plcd
  • Plcd1
  • Plcd
10090
2
  • G protein-coupled receptor signaling pathway
  • GTPase activating protein binding
  • angiogenesis
  • calcium ion binding
  • calcium-dependent phospholipid binding
  • cytoplasm
  • cytosol
  • inositol 1,4,5 trisphosphate binding
  • labyrinthine layer blood vessel development
  • lipid catabolic process
  • mitochondrial membrane
  • phosphatidylinositol metabolic process
  • phosphatidylinositol phospholipase C activity
  • phosphatidylinositol-4,5-bisphosphate binding
  • phosphatidylinositol-mediated signaling
  • phospholipid binding
  • positive regulation of inositol trisphosphate biosynthetic process
  • positive regulation of norepinephrine secretion
  • regulation of cell population proliferation
  • regulation of cytosolic calcium ion concentration
  • release of sequestered calcium ion into cytosol
  • response to calcium ion
  • response to peptide hormone
  • GO:0001525
  • GO:0004435
  • GO:0005509
  • GO:0005543
  • GO:0005544
  • GO:0005546
  • GO:0005737
  • GO:0005829
  • GO:0007186
  • GO:0010701
  • GO:0016042
  • GO:0031966
  • GO:0032794
  • GO:0032962
  • GO:0042127
  • GO:0043434
  • GO:0046488
  • GO:0048015
  • GO:0051209
  • GO:0051480
  • GO:0051592
  • GO:0060716
  • GO:0070679
  • PLCD1
  • PLCD1
9913
2
  • calcium ion binding
  • lipid catabolic process
  • phosphatidylinositol metabolic process
  • phosphatidylinositol phospholipase C activity
  • phosphatidylinositol-4,5-bisphosphate binding
  • phosphatidylinositol-mediated signaling
  • release of sequestered calcium ion into cytosol
  • GO:0004435
  • GO:0005509
  • GO:0005546
  • GO:0016042
  • GO:0046488
  • GO:0048015
  • GO:0051209
  • PLCD1
  • PLCD1
9606
4
1
  • GTPase activating protein binding
  • calcium ion binding
  • cytoplasm
  • extracellular exosome
  • lipid catabolic process
  • phosphatidylinositol metabolic process
  • phosphatidylinositol phospholipase C activity
  • phosphatidylinositol-4,5-bisphosphate binding
  • phosphatidylinositol-mediated signaling
  • phospholipid metabolic process
  • plasma membrane
  • release of sequestered calcium ion into cytosol
  • GO:0004435
  • GO:0005509
  • GO:0005546
  • GO:0005737
  • GO:0005886
  • GO:0006644
  • GO:0016042
  • GO:0032794
  • GO:0046488
  • GO:0048015
  • GO:0051209
  • GO:0070062
  • Plcd1
  • Plcd1
10116
2
1
  • G protein-coupled receptor signaling pathway
  • GTPase activating protein binding
  • angiogenesis
  • calcium ion binding
  • calcium-dependent phospholipid binding
  • cytoplasm
  • cytosol
  • inositol 1,4,5 trisphosphate binding
  • labyrinthine layer blood vessel development
  • lipid catabolic process
  • mitochondrial membrane
  • phosphatidic acid binding
  • phosphatidylinositol metabolic process
  • phosphatidylinositol phosphate binding
  • phosphatidylinositol phospholipase C activity
  • phosphatidylinositol-4,5-bisphosphate binding
  • phosphatidylinositol-mediated signaling
  • phospholipase C activity
  • phospholipid binding
  • positive regulation of inositol trisphosphate biosynthetic process
  • positive regulation of norepinephrine secretion
  • regulation of cell population proliferation
  • regulation of cytosolic calcium ion concentration
  • release of sequestered calcium ion into cytosol
  • response to aluminum ion
  • response to calcium ion
  • response to hyperoxia
  • response to organonitrogen compound
  • response to peptide hormone
  • response to prostaglandin F
  • GO:0001525
  • GO:0004435
  • GO:0004629
  • GO:0005509
  • GO:0005543
  • GO:0005544
  • GO:0005546
  • GO:0005737
  • GO:0005829
  • GO:0007186
  • GO:0010044
  • GO:0010243
  • GO:0010701
  • GO:0016042
  • GO:0031966
  • GO:0032794
  • GO:0032962
  • GO:0034696
  • GO:0042127
  • GO:0043434
  • GO:0046488
  • GO:0048015
  • GO:0051209
  • GO:0051480
  • GO:0051592
  • GO:0055093
  • GO:0060716
  • GO:0070300
  • GO:0070679
  • GO:1901981
  • PLCB4
  • PLCB4
9606
1
  • G protein-coupled receptor signaling pathway
  • calcium ion binding
  • cytosol
  • lipid catabolic process
  • phosphatidylinositol phospholipase C activity
  • phosphatidylinositol-mediated signaling
  • phospholipase C activity
  • release of sequestered calcium ion into cytosol
  • GO:0004435
  • GO:0004629
  • GO:0005509
  • GO:0005829
  • GO:0007186
  • GO:0016042
  • GO:0048015
  • GO:0051209
  • Plcb3
  • Plcb3
10090
1
  • G protein-coupled receptor signaling pathway
  • calcium ion binding
  • calmodulin binding
  • cytosol
  • inositol trisphosphate metabolic process
  • molecular adaptor activity
  • molecular function activator activity
  • nucleus
  • phosphatidylinositol catabolic process
  • phosphatidylinositol metabolic process
  • phosphatidylinositol phospholipase C activity
  • phosphatidylinositol-mediated signaling
  • post-Golgi vesicle-mediated transport
  • postsynaptic cytosol
  • protein-containing complex
  • regulation of systemic arterial blood pressure
  • release of sequestered calcium ion into cytosol
  • sarcolemma
  • GO:0003073
  • GO:0004435
  • GO:0005509
  • GO:0005516
  • GO:0005634
  • GO:0005829
  • GO:0006892
  • GO:0007186
  • GO:0031161
  • GO:0032957
  • GO:0032991
  • GO:0042383
  • GO:0046488
  • GO:0048015
  • GO:0051209
  • GO:0060090
  • GO:0099524
  • GO:0140677
  • PLCB3
  • PLCB3
9606
1
  • G protein-coupled receptor signaling pathway
  • cadherin binding
  • calcium ion binding
  • calmodulin binding
  • cytosol
  • lipid catabolic process
  • membrane
  • molecular adaptor activity
  • molecular function activator activity
  • nucleus
  • phosphatidylinositol metabolic process
  • phosphatidylinositol phospholipase C activity
  • phosphatidylinositol-mediated signaling
  • phospholipase C activity
  • postsynaptic cytosol
  • protein-containing complex
  • regulation of systemic arterial blood pressure
  • release of sequestered calcium ion into cytosol
  • GO:0003073
  • GO:0004435
  • GO:0004629
  • GO:0005509
  • GO:0005516
  • GO:0005634
  • GO:0005829
  • GO:0007186
  • GO:0016020
  • GO:0016042
  • GO:0032991
  • GO:0045296
  • GO:0046488
  • GO:0048015
  • GO:0051209
  • GO:0060090
  • GO:0099524
  • GO:0140677
  • Plcb1
  • Plcb
  • Plcb1
  • Plcb
10090
1
  • G protein-coupled acetylcholine receptor signaling pathway
  • G2/M transition of mitotic cell cycle
  • GABA-ergic synapse
  • GTPase activator activity
  • activation of meiosis involved in egg activation
  • brain development
  • calcium ion binding
  • calmodulin binding
  • cell adhesion
  • cellular response to fluoride
  • cellular response to glyceraldehyde
  • cellular response to ionomycin
  • cellular response to vasopressin
  • cerebral cortex development
  • chromatin
  • cytoplasm
  • enzyme binding
  • erythrocyte differentiation
  • fat cell differentiation
  • glutamate receptor signaling pathway
  • glutamatergic synapse
  • identical protein binding
  • inositol trisphosphate metabolic process
  • insulin receptor signaling pathway
  • insulin-like growth factor receptor signaling pathway
  • interleukin-1-mediated signaling pathway
  • interleukin-12-mediated signaling pathway
  • interleukin-15-mediated signaling pathway
  • ion channel modulating, G protein-coupled receptor signaling pathway
  • lamin binding
  • learning
  • ligand-gated ion channel signaling pathway
  • mRNA processing
  • macrophage differentiation
  • memory
  • myelin sheath
  • negative regulation of DNA-templated transcription
  • negative regulation of monocyte extravasation
  • nuclear membrane
  • nuclear speck
  • nucleus
  • oocyte maturation
  • phosphatidylinositol catabolic process
  • phosphatidylinositol metabolic process
  • phosphatidylinositol phospholipase C activity
  • phosphatidylinositol-4,5-bisphosphate binding
  • phosphatidylinositol-mediated signaling
  • phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway
  • phospholipase C-activating G protein-coupled receptor signaling pathway
  • plasma membrane
  • positive regulation of CD24 production
  • positive regulation of DNA-templated transcription
  • positive regulation of G1/S transition of mitotic cell cycle
  • positive regulation of JNK cascade
  • positive regulation of acrosome reaction
  • positive regulation of developmental growth
  • positive regulation of embryonic development
  • positive regulation of insulin secretion
  • positive regulation of interleukin-12 production
  • positive regulation of myoblast differentiation
  • positive regulation of sodium:proton antiporter activity
  • postsynaptic cytosol
  • postsynaptic modulation of chemical synaptic transmission
  • protein-containing complex
  • regulation of G protein-coupled receptor signaling pathway
  • regulation of establishment of endothelial barrier
  • regulation of fertilization
  • regulation of retrograde trans-synaptic signaling by endocanabinoid
  • release of sequestered calcium ion into cytosol
  • response to monosaccharide
  • response to peptide hormone
  • signal transduction
  • GO:0000086
  • GO:0000785
  • GO:0001556
  • GO:0004435
  • GO:0005096
  • GO:0005509
  • GO:0005516
  • GO:0005521
  • GO:0005546
  • GO:0005634
  • GO:0005737
  • GO:0005886
  • GO:0006397
  • GO:0007155
  • GO:0007165
  • GO:0007200
  • GO:0007207
  • GO:0007213
  • GO:0007215
  • GO:0007420
  • GO:0007612
  • GO:0007613
  • GO:0008277
  • GO:0008286
  • GO:0016607
  • GO:0019899
  • GO:0021987
  • GO:0030218
  • GO:0030225
  • GO:0031161
  • GO:0031965
  • GO:0032024
  • GO:0032417
  • GO:0032735
  • GO:0032957
  • GO:0032991
  • GO:0034284
  • GO:0035722
  • GO:0035723
  • GO:0040019
  • GO:0042802
  • GO:0043209
  • GO:0043434
  • GO:0045444
  • GO:0045663
  • GO:0045892
  • GO:0045893
  • GO:0046330
  • GO:0046488
  • GO:0048009
  • GO:0048015
  • GO:0048639
  • GO:0051209
  • GO:0060466
  • GO:0070498
  • GO:0080154
  • GO:0098978
  • GO:0098982
  • GO:0099105
  • GO:0099170
  • GO:0099178
  • GO:0099524
  • GO:1900087
  • GO:1902618
  • GO:1903140
  • GO:1904117
  • GO:1904637
  • GO:1905631
  • GO:1990806
  • GO:2000344
  • GO:2000438
  • GO:2000560
  • Plcb1
  • Plcb1
10116
1
  • G protein-coupled acetylcholine receptor signaling pathway
  • G2/M transition of mitotic cell cycle
  • GABA-ergic synapse
  • GTPase activator activity
  • activation of meiosis involved in egg activation
  • calcium ion binding
  • calmodulin binding
  • cellular response to fluoride
  • cellular response to glyceraldehyde
  • cellular response to ionomycin
  • cellular response to vasopressin
  • cerebral cortex development
  • chromatin
  • cytoplasm
  • enzyme binding
  • fat cell differentiation
  • glutamate receptor signaling pathway
  • glutamatergic synapse
  • identical protein binding
  • inositol trisphosphate metabolic process
  • insulin-like growth factor receptor signaling pathway
  • interleukin-1-mediated signaling pathway
  • interleukin-12-mediated signaling pathway
  • interleukin-15-mediated signaling pathway
  • ion channel modulating, G protein-coupled receptor signaling pathway
  • lamin binding
  • learning
  • ligand-gated ion channel signaling pathway
  • memory
  • negative regulation of DNA-templated transcription
  • negative regulation of monocyte extravasation
  • nuclear membrane
  • nuclear speck
  • nucleus
  • phosphatidylinositol catabolic process
  • phosphatidylinositol metabolic process
  • phosphatidylinositol phospholipase C activity
  • phosphatidylinositol-4,5-bisphosphate binding
  • phosphatidylinositol-mediated signaling
  • phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway
  • phospholipase C-activating G protein-coupled receptor signaling pathway
  • positive regulation of CD24 production
  • positive regulation of DNA-templated transcription
  • positive regulation of G1/S transition of mitotic cell cycle
  • positive regulation of JNK cascade
  • positive regulation of acrosome reaction
  • positive regulation of developmental growth
  • positive regulation of embryonic development
  • positive regulation of insulin secretion
  • positive regulation of interleukin-12 production
  • positive regulation of myoblast differentiation
  • postsynapse
  • postsynaptic cytosol
  • postsynaptic modulation of chemical synaptic transmission
  • protein-containing complex
  • regulation of G protein-coupled receptor signaling pathway
  • regulation of establishment of endothelial barrier
  • regulation of fertilization
  • regulation of retrograde trans-synaptic signaling by endocanabinoid
  • release of sequestered calcium ion into cytosol
  • response to monosaccharide
  • response to organonitrogen compound
  • response to peptide hormone
  • GO:0000086
  • GO:0000785
  • GO:0004435
  • GO:0005096
  • GO:0005509
  • GO:0005516
  • GO:0005521
  • GO:0005546
  • GO:0005634
  • GO:0005737
  • GO:0007200
  • GO:0007207
  • GO:0007213
  • GO:0007215
  • GO:0007612
  • GO:0007613
  • GO:0008277
  • GO:0010243
  • GO:0016607
  • GO:0019899
  • GO:0021987
  • GO:0031161
  • GO:0031965
  • GO:0032024
  • GO:0032735
  • GO:0032957
  • GO:0032991
  • GO:0034284
  • GO:0035722
  • GO:0035723
  • GO:0040019
  • GO:0042802
  • GO:0043434
  • GO:0045444
  • GO:0045663
  • GO:0045892
  • GO:0045893
  • GO:0046330
  • GO:0046488
  • GO:0048009
  • GO:0048015
  • GO:0048639
  • GO:0051209
  • GO:0060466
  • GO:0070498
  • GO:0080154
  • GO:0098794
  • GO:0098978
  • GO:0098982
  • GO:0099105
  • GO:0099170
  • GO:0099178
  • GO:0099524
  • GO:1900087
  • GO:1902618
  • GO:1903140
  • GO:1904117
  • GO:1904637
  • GO:1905631
  • GO:1990806
  • GO:2000344
  • GO:2000438
  • GO:2000560
  • PLCB1
  • KIAA0581
  • PLCB1
  • KIAA0581
9606
4
1
  • G protein-coupled acetylcholine receptor signaling pathway
  • G protein-coupled receptor signaling pathway
  • G2/M transition of mitotic cell cycle
  • GABA-ergic synapse
  • GTPase activator activity
  • activation of meiosis involved in egg activation
  • calcium ion binding
  • calmodulin binding
  • cellular response to fluoride
  • cellular response to glyceraldehyde
  • cellular response to ionomycin
  • cellular response to vasopressin
  • cerebral cortex development
  • chromatin
  • cytoplasm
  • cytosol
  • enzyme binding
  • extracellular exosome
  • fat cell differentiation
  • glutamate receptor signaling pathway
  • glutamatergic synapse
  • identical protein binding
  • inositol trisphosphate metabolic process
  • insulin-like growth factor receptor signaling pathway
  • interleukin-1-mediated signaling pathway
  • interleukin-12-mediated signaling pathway
  • interleukin-15-mediated signaling pathway
  • ion channel modulating, G protein-coupled receptor signaling pathway
  • lamin binding
  • learning
  • ligand-gated ion channel signaling pathway
  • memory
  • negative regulation of DNA-templated transcription
  • negative regulation of monocyte extravasation
  • nuclear membrane
  • nuclear speck
  • nucleus
  • phosphatidylinositol catabolic process
  • phosphatidylinositol metabolic process
  • phosphatidylinositol phospholipase C activity
  • phosphatidylinositol-4,5-bisphosphate binding
  • phosphatidylinositol-mediated signaling
  • phospholipase C activity
  • phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway
  • positive regulation of CD24 production
  • positive regulation of DNA-templated transcription
  • positive regulation of G1/S transition of mitotic cell cycle
  • positive regulation of JNK cascade
  • positive regulation of acrosome reaction
  • positive regulation of developmental growth
  • positive regulation of embryonic development
  • positive regulation of insulin secretion
  • positive regulation of interleukin-12 production
  • positive regulation of myoblast differentiation
  • postsynaptic cytosol
  • postsynaptic modulation of chemical synaptic transmission
  • regulation of G protein-coupled receptor signaling pathway
  • regulation of establishment of endothelial barrier
  • regulation of fertilization
  • regulation of retrograde trans-synaptic signaling by endocanabinoid
  • release of sequestered calcium ion into cytosol
  • signal transduction
  • GO:0000086
  • GO:0000785
  • GO:0004435
  • GO:0004629
  • GO:0005096
  • GO:0005509
  • GO:0005516
  • GO:0005521
  • GO:0005546
  • GO:0005634
  • GO:0005737
  • GO:0005829
  • GO:0007165
  • GO:0007186
  • GO:0007207
  • GO:0007213
  • GO:0007215
  • GO:0007612
  • GO:0007613
  • GO:0008277
  • GO:0016607
  • GO:0019899
  • GO:0021987
  • GO:0031161
  • GO:0031965
  • GO:0032024
  • GO:0032735
  • GO:0032957
  • GO:0035722
  • GO:0035723
  • GO:0040019
  • GO:0042802
  • GO:0045444
  • GO:0045663
  • GO:0045892
  • GO:0045893
  • GO:0046330
  • GO:0046488
  • GO:0048009
  • GO:0048015
  • GO:0048639
  • GO:0051209
  • GO:0060466
  • GO:0070062
  • GO:0070498
  • GO:0080154
  • GO:0098978
  • GO:0098982
  • GO:0099105
  • GO:0099170
  • GO:0099178
  • GO:0099524
  • GO:1900087
  • GO:1902618
  • GO:1903140
  • GO:1904117
  • GO:1904637
  • GO:1905631
  • GO:1990806
  • GO:2000344
  • GO:2000438
  • GO:2000560
Displaying entries 120111 - 120120 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01