GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Protein adenylyltransferase FICD (Fragment)	A0A7K8JBH1	Ficd		Ficd	Chaetorhynchus papuensis	254446	1	ATP binding nucleotidyltransferase activity	GO:0005524 GO:0016779
Matrix protein 2	A0A1D8HD70	M2	M	M2 M	Influenza A virus (A/North Carolina/41/2016(H3N2))	1910104	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Ribonuclease K6	O46530	RNASE6		RNASE6	Saguinus oedipus	9490	2	defense response to bacterium endonuclease activity extracellular region lysosome nucleic acid binding	GO:0003676 GO:0004519 GO:0005576 GO:0005764 GO:0042742
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase	A0A8K1LJ21	HGM15179_011635		HGM15179_011635	Zosterops borbonicus	364589	1	Golgi membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity metal ion binding	GO:0000139 GO:0015018 GO:0046872
Cathepsin D (Fragment)	A0A093EST4	N341_03534		N341_03534	Tyto alba	56313	2	aspartic-type endopeptidase activity lysosome proteolysis	GO:0004190 GO:0005764 GO:0006508
ABC-type transporter claG	A0A481WQK1	claG		claG	Penicillium crustosum	36656	3	ABC-type transporter activity ATP binding ATP hydrolysis activity membrane	GO:0005524 GO:0016020 GO:0016887 GO:0140359
P2X purinoceptor	A0A7J6D3L6	G5714_006336		G5714_006336	Onychostoma macrolepis	369639	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
Class V chitinase CHIT5	A0A1B1J8Z2	CHIT5		CHIT5	Lotus japonicus	34305	6	chitin binding chitin catabolic process chitinase activity defense response to fungus nodulation polysaccharide catabolic process	GO:0000272 GO:0004568 GO:0006032 GO:0008061 GO:0009877 GO:0050832
Xyloglucan endotransglucosylase/hydrolase	A0A835E3N4	HU200_059348		HU200_059348	Digitaria exilis	1010633	1	apoplast cell wall biogenesis cell wall organization hydrolase activity, hydrolyzing O-glycosyl compounds xyloglucan metabolic process xyloglucan:xyloglucosyl transferase activity	GO:0004553 GO:0010411 GO:0016762 GO:0042546 GO:0048046 GO:0071555
Interleukin-2	O77620	IL2		IL2	Oryctolagus cuniculus	9986	2	activated T cell proliferation adaptive immune response cytokine activity extracellular space extrinsic apoptotic signaling pathway in absence of ligand growth factor activity interleukin-2 receptor binding interleukin-2-mediated signaling pathway leukocyte activation involved in immune response negative regulation of B cell apoptotic process negative regulation of T-helper 17 cell differentiation negative regulation of inflammatory response negative regulation of lymphocyte proliferation positive regulation of B cell proliferation positive regulation of activated T cell proliferation positive regulation of interleukin-17 production positive regulation of isotype switching to IgG isotypes positive regulation of plasma cell differentiation positive regulation of transcription by RNA polymerase II positive regulation of type II interferon production positive regulation of tyrosine phosphorylation of STAT protein regulation of CD4-positive, alpha-beta T cell proliferation regulation of T cell homeostatic proliferation transcription by RNA polymerase II	GO:0002250 GO:0002366 GO:0002903 GO:0005125 GO:0005134 GO:0005615 GO:0006366 GO:0008083 GO:0030890 GO:0032729 GO:0032740 GO:0038110 GO:0042104 GO:0042531 GO:0045944 GO:0046013 GO:0048304 GO:0050672 GO:0050728 GO:0050798 GO:0097192 GO:1900100 GO:2000320 GO:2000561