GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GO Labels	GO IDs
Cadherin-13	Q3B7N0	CDH13		CDH13	Bos taurus	9913	9		adherens junction adherens junction organization cadherin binding calcium ion binding calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules catenin complex cell morphogenesis cell-cell adhesion mediated by cadherin cell-cell junction assembly homophilic cell adhesion via plasma membrane adhesion molecules side of membrane sprouting angiogenesis	GO:0000902 GO:0002040 GO:0005509 GO:0005912 GO:0007043 GO:0007156 GO:0016339 GO:0016342 GO:0034332 GO:0044331 GO:0045296 GO:0098552
Non-structural glycoprotein 4	T1RQF3	NSP4		NSP4	Avian rotavirus A	31563	1		extracellular region host caveola host cell rough endoplasmic reticulum membrane induction by virus of host autophagy membrane metal ion binding monoatomic ion channel activity protein complex oligomerization toxin activity virus-mediated pore formation in host cell membrane	GO:0005216 GO:0005576 GO:0016020 GO:0039520 GO:0039707 GO:0044155 GO:0044169 GO:0046872 GO:0051259 GO:0090729
Liprin-alpha-3	O75145	PPFIA3	KIAA0654	PPFIA3 KIAA0654	Homo sapiens	9606	1	1	acrosomal vesicle cytosol epididymosome glutamatergic synapse neurotransmitter secretion presynaptic active zone presynaptic active zone cytoplasmic component regulation of short-term neuronal synaptic plasticity synapse organization synaptic vesicle docking	GO:0001669 GO:0005829 GO:0007269 GO:0016081 GO:0048172 GO:0048786 GO:0050808 GO:0098831 GO:0098875 GO:0098978
Lymphotoxin-alpha	P61125	LTA	TNFB TNFSF1	LTA TNFB TNFSF1	Pan troglodytes	9598	2		cytokine activity defense response to Gram-positive bacterium extracellular space humoral immune response lymph node development membrane positive regulation of chronic inflammatory response to antigenic stimulus positive regulation of humoral immune response mediated by circulating immunoglobulin positive regulation of type II interferon production tumor necrosis factor receptor binding	GO:0002876 GO:0002925 GO:0005125 GO:0005164 GO:0005615 GO:0006959 GO:0016020 GO:0032729 GO:0048535 GO:0050830
Matrix protein 2	A0A0N9RC62	M2	M	M2 M	Influenza A virus (A/Vermont/06/2015(H3N2))	1731875	1		host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Matrix protein 2	H8P175	M2	M	M2 M	Influenza A virus (A/Western Australia/33/2002(H3N2))	390188	1		host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Peptidylglycine alpha-amidating monooxygenase	A0A8C7BRJ2	PAM		PAM	Neogale vison	452646	1		L-ascorbic acid binding copper ion binding lyase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen peptide metabolic process transport vesicle membrane	GO:0005507 GO:0006518 GO:0016715 GO:0016829 GO:0030658 GO:0031418
glucuronosyltransferase	H2KZP8	ugt-39		ugt-39	Caenorhabditis elegans	6239	1		UDP-glycosyltransferase activity glucuronosyltransferase activity membrane	GO:0008194 GO:0015020 GO:0016020
Zona pellucida sperm-binding protein 3	P48832	ZP3	ZPC	ZP3 ZPC	Felis catus	9685	6		acrosin binding binding of sperm to zona pellucida blastocyst formation carbohydrate binding collagen-containing extracellular matrix egg coat egg coat formation extracellular matrix extracellular space humoral immune response mediated by circulating immunoglobulin negative regulation of DNA-templated transcription negative regulation of binding of sperm to zona pellucida oocyte development plasma membrane positive regulation of DNA-templated transcription positive regulation of T cell proliferation positive regulation of acrosomal vesicle exocytosis positive regulation of acrosome reaction positive regulation of antral ovarian follicle growth positive regulation of humoral immune response positive regulation of inflammatory response positive regulation of interleukin-4 production positive regulation of leukocyte migration positive regulation of ovarian follicle development positive regulation of type II interferon production positive regulation of type IV hypersensitivity receptor ligand activity structural constituent of egg coat	GO:0001809 GO:0001825 GO:0002455 GO:0002687 GO:0002922 GO:0005615 GO:0005886 GO:0007339 GO:0030246 GO:0031012 GO:0032190 GO:0032729 GO:0032753 GO:0035803 GO:0035804 GO:0035805 GO:0042102 GO:0045892 GO:0045893 GO:0048018 GO:0048599 GO:0050729 GO:0062023 GO:2000344 GO:2000360 GO:2000368 GO:2000386 GO:2000388
Podocalyxin	O00592	PODXL	PCLP PCLP1	PODXL PCLP PCLP1	Homo sapiens	9606	72	30	apical plasma membrane cell adhesion cell migration centriolar satellite cytoplasm epithelial tube formation extracellular exosome extracellular space filopodium intracellular membrane-bounded organelle lamellipodium membrane raft microvillus membrane negative regulation of cell adhesion negative regulation of cell-cell adhesion nucleolus plasma membrane podocyte development positive regulation of cell migration positive regulation of cell-cell adhesion mediated by integrin regulation of microvillus assembly ruffle slit diaphragm	GO:0001726 GO:0005615 GO:0005730 GO:0005737 GO:0005886 GO:0007155 GO:0007162 GO:0016324 GO:0016477 GO:0022408 GO:0030027 GO:0030175 GO:0030335 GO:0031528 GO:0032534 GO:0033634 GO:0034451 GO:0036057 GO:0043231 GO:0045121 GO:0070062 GO:0072015 GO:0072175