GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites ▼	No. of GlyTouCan IDs	Disease Name	Aliases Disease Name	GO Labels	GO IDs
Hemicentin-2	Q8NDA2	HMCN2		HMCN2	Homo sapiens	9606	40				axon axon guidance receptor activity calcium ion binding cleavage furrow collagen-containing extracellular matrix extracellular region homophilic cell adhesion via plasma membrane adhesion molecules neuronal cell body plasma membrane synapse organization	GO:0005509 GO:0005576 GO:0005886 GO:0007156 GO:0008046 GO:0030424 GO:0032154 GO:0043025 GO:0050808 GO:0062023
Glucoamylase	P22832	glaA	gla	glaA gla	Aspergillus usamii	186680	40				glucan 1,4-alpha-glucosidase activity polysaccharide catabolic process starch binding	GO:0000272 GO:0004339 GO:2001070
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta	Q3T906	GNPTAB	GNPTA KIAA1208	GNPTAB GNPTA KIAA1208	Homo sapiens	9606	40	9	Mucolipidosis II (alpha/beta) Mucolipidosis III (alpha/beta)	I-cell disease ML-II ML-III N-Acetylglucosamine-1-phosphotransferase deficiency Pseudo-Hurler Polydystrophy	Golgi apparatus Golgi membrane N-glycan processing to lysosome UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity calcium ion binding carbohydrate phosphorylation lysosome organization secretion of lysosomal enzymes	GO:0000139 GO:0003976 GO:0005509 GO:0005794 GO:0007040 GO:0016256 GO:0033299 GO:0046835
Reticulocyte-binding protein homolog 2b	C0H5F4	RH2b		RH2b	Plasmodium falciparum 3D7	36329	40				adhesion of symbiont to host cell apical plasma membrane cell-cell adhesion cytoplasmic vesicle entry into host extracellular space heparin binding host cell surface receptor binding host-symbiont bicellular tight junction membrane plasma membrane rhoptry rhoptry neck tight junction	GO:0005615 GO:0005886 GO:0008201 GO:0016020 GO:0016324 GO:0020008 GO:0031410 GO:0044409 GO:0044647 GO:0044650 GO:0046789 GO:0070160 GO:0098609 GO:1990225
Receptor-type tyrosine-protein phosphatase zeta	P23471	PTPRZ1	HTPZP2 PTPRZ PTPRZ2 PTPZ	PTPRZ1 HTPZP2 PTPRZ PTPRZ2 PTPZ	Homo sapiens	9606	40	6			axonogenesis central nervous system development extracellular region hematopoietic progenitor cell differentiation integrin binding learning or memory negative regulation of neuron apoptotic process oligodendrocyte differentiation peptidyl-tyrosine dephosphorylation perineuronal net plasma membrane positive regulation of oligodendrocyte differentiation protein dephosphorylation protein tyrosine phosphatase activity regulation of myelination regulation of oligodendrocyte progenitor proliferation synapse transmembrane receptor protein tyrosine phosphatase activity	GO:0002244 GO:0004725 GO:0005001 GO:0005178 GO:0005576 GO:0005886 GO:0006470 GO:0007409 GO:0007417 GO:0007611 GO:0031641 GO:0035335 GO:0043524 GO:0045202 GO:0048709 GO:0048714 GO:0070445 GO:0072534
Protein PIEZO homolog	Q54S52	DDB_G0282801		DDB_G0282801	Dictyostelium discoideum	44689	40				cellular response to mechanical stimulus detection of mechanical stimulus mechanosensitive monoatomic cation channel activity mechanosensitive monoatomic ion channel activity membrane monoatomic cation channel activity regulation of membrane potential	GO:0005261 GO:0008381 GO:0016020 GO:0042391 GO:0050982 GO:0071260 GO:0140135
Protocadherin Fat 2	Q9NYQ8	FAT2	CDHF8 KIAA0811 MEGF1	FAT2 CDHF8 KIAA0811 MEGF1	Homo sapiens	9606	40	2			Golgi apparatus adherens junction calcium ion binding cell-cell adhesion cell-substrate adhesion epithelial cell migration extracellular exosome homophilic cell adhesion via plasma membrane adhesion molecules plasma membrane	GO:0005509 GO:0005794 GO:0005886 GO:0005912 GO:0007156 GO:0010631 GO:0031589 GO:0070062 GO:0098609
CUB and sushi domain-containing protein 1	Q96PZ7	CSMD1	KIAA1890	CSMD1 KIAA1890	Homo sapiens	9606	40				conditioned place preference female gonad development glucose homeostasis male gonad development mammary gland branching involved in pregnancy membrane memory oviduct epithelium development startle response	GO:0001964 GO:0007613 GO:0008584 GO:0008585 GO:0016020 GO:0035846 GO:0042593 GO:0060745 GO:1990708
CUB and sushi domain-containing protein 1	Q923L3	Csmd1		Csmd1	Mus musculus	10090	40	7			conditioned place preference female gonad development glucose homeostasis male gonad development mammary gland branching involved in pregnancy membrane memory oviduct epithelium development startle response	GO:0001964 GO:0007613 GO:0008584 GO:0008585 GO:0016020 GO:0035846 GO:0042593 GO:0060745 GO:1990708
LIM domain only protein 7	Q8WWI1	LMO7	FBX20 FBXO20 KIAA0858	LMO7 FBX20 FBXO20 KIAA0858	Homo sapiens	9606	40	2			apical plasma membrane cell surface cytoplasm cytosol focal adhesion metal ion binding nuclear envelope nucleus positive regulation of transcription by RNA polymerase II protein ubiquitination regulation of cell adhesion regulation of signaling ubiquitin ligase complex ubiquitin-protein transferase activity	GO:0000151 GO:0004842 GO:0005634 GO:0005635 GO:0005737 GO:0005829 GO:0005925 GO:0009986 GO:0016324 GO:0016567 GO:0023051 GO:0030155 GO:0045944 GO:0046872