GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Gene Symbol All	Species	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs ▼	GO Labels	GO IDs
Myeloperoxidase	P05164	MPO		MPO	Homo sapiens	9606	8	38	azurophil granule azurophil granule lumen chromatin binding defense response defense response to bacterium defense response to fungus extracellular exosome extracellular region extracellular space heme binding heparin binding hydrogen peroxide catabolic process hypochlorous acid biosynthetic process intracellular membrane-bounded organelle low-density lipoprotein particle remodeling lysosome metal ion binding negative regulation of apoptotic process nucleoplasm nucleus peroxidase activity phagocytic vesicle lumen removal of superoxide radicals respiratory burst involved in defense response response to food response to gold nanoparticle response to lipopolysaccharide response to mechanical stimulus response to oxidative stress response to yeast secretory granule	GO:0001878 GO:0002149 GO:0002679 GO:0003682 GO:0004601 GO:0005576 GO:0005615 GO:0005634 GO:0005654 GO:0005764 GO:0006952 GO:0006979 GO:0008201 GO:0009612 GO:0019430 GO:0020037 GO:0030141 GO:0032094 GO:0032496 GO:0034374 GO:0035578 GO:0042582 GO:0042742 GO:0042744 GO:0043066 GO:0043231 GO:0046872 GO:0050832 GO:0070062 GO:0097013 GO:1990268
Prostaglandin F2 receptor negative regulator	Q9P2B2	PTGFRN	CD9P1 EWIF FPRP KIAA1436	PTGFRN CD9P1 EWIF FPRP KIAA1436	Homo sapiens	9606	12	37	Golgi apparatus cell surface endoplasmic reticulum membrane lipid droplet organization myoblast fusion involved in skeletal muscle regeneration	GO:0005789 GO:0005794 GO:0009986 GO:0014905 GO:0034389
WAP four-disulfide core domain protein 2	Q14508	WFDC2	HE4 WAP5	WFDC2 HE4 WAP5	Homo sapiens	9606	2	37	antibacterial humoral response aspartic-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity endopeptidase inhibitor activity extracellular exosome extracellular space innate immune response proteolysis serine-type endopeptidase inhibitor activity spermatogenesis	GO:0004866 GO:0004867 GO:0004869 GO:0005615 GO:0006508 GO:0007283 GO:0019731 GO:0019828 GO:0045087 GO:0070062
Uncharacterized protein (Fragment)	Q3TRA6	Atp1b1		Atp1b1	Mus musculus	10090	2	36	potassium ion transport sodium ion transport sodium:potassium-exchanging ATPase complex	GO:0005890 GO:0006813 GO:0006814
Multimerin-1	Q13201	MMRN1	ECM EMILIN4 GPIA* MMRN	MMRN1 ECM EMILIN4 GPIA* MMRN	Homo sapiens	9606	28	36	blood coagulation calcium ion binding cell adhesion cell adhesion mediated by integrin collagen-containing extracellular matrix extracellular matrix constituent conferring elasticity extracellular region multimerin complex negative regulation of wound healing platelet alpha granule platelet alpha granule lumen positive regulation of platelet aggregation	GO:0005509 GO:0005576 GO:0007155 GO:0007596 GO:0030023 GO:0031091 GO:0031093 GO:0033627 GO:0061045 GO:0062023 GO:1901731 GO:1990972
Sodium/potassium-transporting ATPase subunit beta	Q3TV47	Atp1b1		Atp1b1	Mus musculus	10090	3	36	potassium ion transport sodium ion transport sodium:potassium-exchanging ATPase complex	GO:0005890 GO:0006813 GO:0006814
Sodium/potassium-transporting ATPase subunit beta	Q545P0	Atp1b1		Atp1b1	Mus musculus	10090	3	36	ATP metabolic process ATPase activator activity ATPase binding T-tubule apical plasma membrane intracellular potassium ion homeostasis intracellular sodium ion homeostasis lateral plasma membrane membrane repolarization organelle membrane positive regulation of potassium ion import across plasma membrane positive regulation of sodium ion export across plasma membrane potassium ion transport protein localization to plasma membrane protein stabilization protein-macromolecule adaptor activity sodium ion export across plasma membrane sodium:potassium-exchanging ATPase complex sperm flagellum	GO:0001671 GO:0005890 GO:0006813 GO:0006883 GO:0016324 GO:0016328 GO:0030007 GO:0030315 GO:0030674 GO:0031090 GO:0036126 GO:0036376 GO:0046034 GO:0050821 GO:0051117 GO:0072659 GO:0086009 GO:1903278 GO:1903288
Envelope glycoprotein gp160	Q70626	env		env	Human immunodeficiency virus type 1 lw12.3 isolate	82834	29	36	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Golgi membrane protein 1	Q8NBJ4	GOLM1	C9orf155 GOLPH2	GOLM1 C9orf155 GOLPH2	Homo sapiens	9606	18	36	Golgi apparatus endoplasmic reticulum lumen extracellular space nucleus organization plasma membrane regulation of lipid metabolic process	GO:0005615 GO:0005788 GO:0005794 GO:0005886 GO:0006997 GO:0019216
Monocyte differentiation antigen CD14	P08571	CD14		CD14	Homo sapiens	9606	7	36	Golgi apparatus apoptotic process cell surface pattern recognition receptor signaling pathway cell surface receptor signaling pathway cellular response to diacyl bacterial lipopeptide cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to molecule of bacterial origin cellular response to triacyl bacterial lipopeptide endosome membrane external side of plasma membrane extracellular exosome extracellular region extracellular space inflammatory response innate immune response lipopolysaccharide binding lipopolysaccharide immune receptor activity lipopolysaccharide receptor complex lipoteichoic acid binding membrane raft opsonin receptor activity peptidoglycan immune receptor activity phagocytosis plasma membrane positive regulation of cytokine production positive regulation of endocytosis positive regulation of interleukin-8 production positive regulation of lipopolysaccharide-mediated signaling pathway positive regulation of toll-like receptor 4 signaling pathway positive regulation of tumor necrosis factor production positive regulation of type I interferon production positive regulation of type II interferon production receptor-mediated endocytosis response to electrical stimulus response to ethanol response to magnesium ion response to tumor necrosis factor secretory granule membrane toll-like receptor 4 signaling pathway	GO:0001530 GO:0001819 GO:0001847 GO:0001875 GO:0002752 GO:0005576 GO:0005615 GO:0005794 GO:0005886 GO:0006898 GO:0006909 GO:0006915 GO:0006954 GO:0007166 GO:0009897 GO:0010008 GO:0016019 GO:0030667 GO:0031666 GO:0032026 GO:0032481 GO:0032729 GO:0032757 GO:0032760 GO:0034142 GO:0034145 GO:0034612 GO:0045087 GO:0045121 GO:0045471 GO:0045807 GO:0046696 GO:0051602 GO:0070062 GO:0070891 GO:0071219 GO:0071222 GO:0071223 GO:0071726 GO:0071727